Multicomponent Exercise on Executive Function and Balance

Overview

The present study is to examine the effects of a multicomponent exercise on executive function and balance in pre-frail older adults.

Full Title of Study: “Effects of A Multicomponent Exercise on Executive Function and Balance in Pre-frail Older Adults”

Study Type

• Study Type: Interventional
• Study Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Primary Purpose: Prevention
  • Masking: Single (Outcomes Assessor)
• Study Primary Completion Date: July 31, 2019

Interventions

• Other: Multicomponent exercise
  • Aerobic exercise: 15~20 mins Resistance exercise: 15 mins Balance exercise: 15~20 mins Flexibility exercise: 10 mins
• Other: Home-program exercise
  • 60 mins exercise

Arms, Groups and Cohorts

• Experimental: Multicomponent exercise group
• Active Comparator: Home-program exercise group

Clinical Trial Outcome Measures

Primary Measures

• Trail-Making test
  • Time Frame: Change from baseline at 12 weeks
  • Executive function
• Stroop test
  • Time Frame: Change from baseline at 12 weeks
  • Executive function
• Digit span test
  • Time Frame: Change from baseline at 12 weeks
  • Executive function
• Mini-Balance Evaluation Systems Test
  • Time Frame: Change from baseline at 12 weeks
  • Balance
• Time Up & Go test
  • Time Frame: Change from baseline at 12 weeks
  • Balance
• One leg standing test
  • Time Frame: Change from baseline at 12 weeks
  • Balance

Secondary Measures

• Montreal Cognitive Assessment
  • Time Frame: Change from Baseline at 12 weeks
  • Global cognition
• Fried frailty criteria
  • Time Frame: Change from baseline at 12 weeks
  • Frailty reverse

Participating in This Clinical Trial

Inclusion Criteria

• Age≥ 65 – Pre-frail according to the Fried Physical Frailty Phenotype – Community-dwelling and able to walk independently>6m Exclusion Criteria:

• Unstable medical condition (ACSM Health Facility Pre-participation Screening Questionnaire) – Neurological conditions(eg, Parkinson's disease, stroke, multiple sclerosis) – MMSE<24 – Visual or color discrimination impairment

Gender Eligibility: All

Minimum Age: 65 Years

Maximum Age: 100 Years

Are Healthy Volunteers Accepted: No

Investigator Details

• Lead Sponsor
  • National Yang Ming University
• Provider of Information About this Clinical Study
  • Principal Investigator: Yea-Ru Yang, Professor – National Yang Ming University