Serum Preptin and Amylin Levels in Polycystic Ovary Syndrome Patients

Overview

Preptin and amylin are pancreatic hormones which participate in glucose homeostasis. This study aims to evaluate how serum preptin and amylin levels are altered in polycystic ovary syndrome (PCOS) patients and healthy women based on BMI groups .

Full Title of Study: “Serum Preptin and Amylin Levels With Respect to Body Mass Index in Polycystic Ovary”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: November 30, 2017

Detailed Description

Materials and Methods: This is a cross-sectional review of 40 PCOS patients and 40 healthy women who were matched with respect to BMI (<25 kg/m2 and ≥25 kg/m2).

Interventions

  • Diagnostic Test: preptin and amylin level
    • we will take both of group blood samples to compare them serum preptin and amylin

Arms, Groups and Cohorts

  • Polycyctic ovary sendrome (PCOS)
    • these women who have PCOS, we will use their blood samples
  • Healty groups
    • These women who have reguler menstrual cycle, no akne or hirsutism, we will use their boold samples

Clinical Trial Outcome Measures

Primary Measures

  • Serum Preptin and Amylin Levels with Respect to Body Mass Index in Polycystic Ovary Syndrome Patients
    • Time Frame: six months
    • Serum Preptin and Amylin Levels will compare between groups

Participating in This Clinical Trial

Inclusion Criteria

the patients with PCOS

Exclusion Criteria

Cushing's syndrome 21-hydroxylase deficiency Congenital adrenal hyperplasia Thyroid dysfunction Hyperprolactinemia Diabetes Chronic cardiovascular Hepatic, renal, and hematologic diseases Malignancies Using oral contraceptives, anti-androgens, glucocorticoids, anti-hypertensives, anti-diabetics, calcium supplements and anti-obesity drugs and those who smoke or consume alcohol

Gender Eligibility: Female

Minimum Age: 17 Years

Maximum Age: 35 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Recep Tayyip Erdogan University Training and Research Hospital
  • Provider of Information About this Clinical Study
    • Principal Investigator: Senol Senturk, Serum Preptin and Amylin Levels in Polycystic Ovary Syndrome Patients – Recep Tayyip Erdogan University Training and Research Hospital
  • Overall Official(s)
    • Senol sentürk, PhD, Study Director, Recep Tayyip Erdogan University

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