The Brugada Syndrome: a Follow-up Study

Overview

Although for many years the Brugada syndrome has been labelled as a purely electrical disease in the structurally normal heart, the evolution of imaging techniques has enabled the discovery of subtle morphofunctional alterations in some of the Brugada syndrome patients. We will use new echocardiographic techniques to assess cardiac function in these patients and new parameters will be evaluated for their prognostic value as risk stratificators.

Full Title of Study: “Imaging and Risk Stratification in the Brugada Syndrome: a Follow-up Study”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: September 2018

Interventions

  • Diagnostic Test: Transthoracic echocardiography
    • Transthoracic echocardiography Blood sample with assessment of biomarkers

Clinical Trial Outcome Measures

Primary Measures

  • Composed outcome of sudden cardiac death, appropriate ICD shock and witnessed ventricular fibrillation
    • Time Frame: 6 years
    • Sudden cardiac death is death occuring within 24 hours after being seen in a healthy status or within 1 hour after initiation of symptoms.

Secondary Measures

  • Syncope
    • Time Frame: 6 years
    • Loss of consciousness

Participating in This Clinical Trial

Inclusion Criteria

  • 18 years or older – Diagnosis of Brugada syndrome Exclusion Criteria:

  • history of pericarditis, ischemic heart disease, cardiomyopathy of any origin, structural heart disease, or any other channelopathy

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Universitair Ziekenhuis Brussel
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Contact(s)
    • Esther Scheirlynck, esther.scheirlynck@uzbrussel.be

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.