Evaluation by MRI of Anal Canal Cell Carcinoma: is There Predictive Factor?

Overview

Anal canal cell carcinoma is a very rare cancer but well treated. If the morphological test are well established in the initial evaluation, it's not the case of the follow up evaluation particularly by MRI.About 1/3 of patient decline with metastatic relapse during the follow up of these patients.It appears that clinical regression seen precociously is a predictive factor of survival without relapse. But there 's no study confirming that point.

This context takes us to evaluate if there is a predictive factor in MRI to final clinical result.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: May 1, 2017

Interventions

  • Diagnostic Test: MRI sequence
    • several MRI sequence before and after contrast product injection.

Clinical Trial Outcome Measures

Primary Measures

  • Distance with regard to the anal margin
    • Time Frame: maximum of 6 years after the initial MRI
    • tumor position
  • initial tumor size
    • Time Frame: maximum of 6 years after the initial MRI
    • Maximal tumoral size in the cranio-caudal plan in cm
  • presence of nodal status
    • Time Frame: maximum of 6 years after the initial MRI
    • presence of nodal status in inguinal region

Participating in This Clinical Trial

Inclusion Criteria

  • patient with anal canal cell carcinoma histologically proved
  • patient with initial MRI and follow up MRI in Hospital St Joseph's radiology yard.
  • patient for whom a radio chemotherapy treatment decision was taken.

Exclusion Criteria

  • patients with already metastatic lesions

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Groupe Hospitalier Paris Saint Joseph
  • Provider of Information About this Clinical Study
    • Sponsor

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.