Evaluation by MRI of Anal Canal Cell Carcinoma: is There Predictive Factor?


Anal canal cell carcinoma is a very rare cancer but well treated. If the morphological test are well established in the initial evaluation, it's not the case of the follow up evaluation particularly by MRI.About 1/3 of patient decline with metastatic relapse during the follow up of these patients.It appears that clinical regression seen precociously is a predictive factor of survival without relapse. But there 's no study confirming that point.

This context takes us to evaluate if there is a predictive factor in MRI to final clinical result.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: May 1, 2017


  • Diagnostic Test: MRI sequence
    • several MRI sequence before and after contrast product injection.

Clinical Trial Outcome Measures

Primary Measures

  • Distance with regard to the anal margin
    • Time Frame: maximum of 6 years after the initial MRI
    • tumor position
  • initial tumor size
    • Time Frame: maximum of 6 years after the initial MRI
    • Maximal tumoral size in the cranio-caudal plan in cm
  • presence of nodal status
    • Time Frame: maximum of 6 years after the initial MRI
    • presence of nodal status in inguinal region

Participating in This Clinical Trial

Inclusion Criteria

  • patient with anal canal cell carcinoma histologically proved
  • patient with initial MRI and follow up MRI in Hospital St Joseph's radiology yard.
  • patient for whom a radio chemotherapy treatment decision was taken.

Exclusion Criteria

  • patients with already metastatic lesions

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Groupe Hospitalier Paris Saint Joseph
  • Provider of Information About this Clinical Study
    • Sponsor

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