New Insights Into the Metabolic Syndrome: the Role of Alpha Defensin

Overview

The purpose of this study is to find out if there is a connection between a higher level of peptide alpha defensin in blood serum with the metabolic profile of adolescents aged 13-17.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Non-Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Screening
    • Masking: None (Open Label)
  • Study Primary Completion Date: September 2019

Interventions

  • Diagnostic Test: Serum blood
    • Serum blood test for laboratory analysis to determine level of alpha defensin

Arms, Groups and Cohorts

  • Active Comparator: BMI above 95%
    • Serum blood will be taken from obese youths with suspected metabolic syndrome
  • Active Comparator: BMI below 3%
    • Serum blood will be taken from slim youths

Clinical Trial Outcome Measures

Primary Measures

  • Alpha defensin level
    • Time Frame: 2 hours
    • Alpha defensin level above 12ng/microliter

Participating in This Clinical Trial

Inclusion Criteria

  • Youths with metabolic syndrome (BMI above 95%) – Youths with BMI below 3% Exclusion Criteria:

-

Gender Eligibility: All

Minimum Age: 13 Years

Maximum Age: 17 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Hillel Yaffe Medical Center
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Eias Kassem, MD, Principal Investigator, Hillel Yaffe Medical Center
  • Overall Contact(s)
    • Eias Kassem, MD, 972-50-6246882, eiask@hy.health.gov.il

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.