New Insights Into the Metabolic Syndrome: the Role of Alpha Defensin
Overview
The purpose of this study is to find out if there is a connection between a higher level of peptide alpha defensin in blood serum with the metabolic profile of adolescents aged 13-17.
Study Type
- Study Type: Interventional
- Study Design
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Primary Purpose: Screening
- Masking: None (Open Label)
- Study Primary Completion Date: September 2019
Interventions
- Diagnostic Test: Serum blood
- Serum blood test for laboratory analysis to determine level of alpha defensin
Arms, Groups and Cohorts
- Active Comparator: BMI above 95%
- Serum blood will be taken from obese youths with suspected metabolic syndrome
- Active Comparator: BMI below 3%
- Serum blood will be taken from slim youths
Clinical Trial Outcome Measures
Primary Measures
- Alpha defensin level
- Time Frame: 2 hours
- Alpha defensin level above 12ng/microliter
Participating in This Clinical Trial
Inclusion Criteria
- Youths with metabolic syndrome (BMI above 95%) – Youths with BMI below 3% Exclusion Criteria:
-
Gender Eligibility: All
Minimum Age: 13 Years
Maximum Age: 17 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- Hillel Yaffe Medical Center
- Provider of Information About this Clinical Study
- Sponsor
- Overall Official(s)
- Eias Kassem, MD, Principal Investigator, Hillel Yaffe Medical Center
- Overall Contact(s)
- Eias Kassem, MD, 972-50-6246882, eiask@hy.health.gov.il
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