Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital

Overview

With 24 million results associated with Google's searchon keywords "severe acne", Pr Dreno's team understand better thatthis disease, which affects many French people, is a real concern of Public Health and not a "forced evil" of the adolescent period, which will eventually resolve itself. Acne does not affect the vital prognosis, but its psychosocial impact is major and should not be underestimated. Paradoxically, despite the high prevalence of acne, few quality epidemiological studies have been published. Physicians are often helpless when faced with patients' questions. They often need a lot of explanations, especially on the factors aggravating this dermatosis, which greatly affects their quality of life. This cohort, the first of its kind in France, will determine the predictive factors of therapeutic response, endogenous and environmental factors impacting on the severity of acne assess the quality of life and psychological impact of acne patients, determine the patient's course of care and the associated costs. Pr Dreno's team will also build up a bio collection (bacteriological samples).

Full Title of Study: “Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital: the COPACNE Cohort.”

Study Type

  • Study Type: Observational [Patient Registry]
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: February 28, 2033

Detailed Description

All patients going for the first time in specialized consultation "acne" at Nantes University Hospital , and who meet the inclusion criteria will be included in the COPACNE cohort. Inclusion will take place at the first consultation, after information and agreement of the patient and, if applicable, his or her legal representatives. The frequency of each patient's follow-up visits will be determined on a case-by-case basis according to the patient's medical needs (generally, the interval between 2 visits is between 1 and 4 months).

Interventions

  • Other: acne
    • Patient with acne

Clinical Trial Outcome Measures

Primary Measures

  • Measure of Acne stage
    • Time Frame: 2 years
    • composite criteria. the scale is GEA for Global Evaluation Acne Scale with 0 no acne to 5 severe acne

Secondary Measures

  • assessing patients’ quality of life
    • Time Frame: 2 years
    • composite criteria. CADI score is calculated by summing the score of each question resulting in a possible maximum of 15 and a minimum of 0. The higher the score, the more the quality of life is impaired.
  • cost of acne illness
    • Time Frame: 2 years
    • reimbursement data relating to hospitalizations and care in town recorded by the Health Insurance in the SNIIRAM database.
  • Bacteriological sample to find Propionibacterium acnes, Hormonal check-up on blood sample
    • Time Frame: 2 years
    • Correlation between bacterial and blood samples and the efficacity of the treatment

Participating in This Clinical Trial

Inclusion Criteria

  • Patient with acne – Patient (or parents/guardians for minors) who are not opposed to participating in the cohort. – Subjects affiliated to an appropriate health insurance Exclusion Criteria:

  • Dermatosis of the face other than acne – Refusal to participate by the minor or parent/guardian – Adults under a legal protection regime (guardianship, trusteeship, judicial safeguard)

Gender Eligibility: All

Minimum Age: N/A

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Nantes University Hospital
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Brigitte DRENO, PU-PH, Principal Investigator, Nantes University Hospital
  • Overall Contact(s)
    • Brigitte DRENO, 0240083137, brigitte.dreno@wanadoo.fr

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