Mini-autogenous Skin Grafts With Skin Homografts Versus Autogenous Skin Graft for Covering Post Burn Wounds in Children

Overview

A prospective study comparing the use of mini-autogenous skin grafts and skin homograft versus autogenous skin grafts for covering post burn wounds in children.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Factorial Assignment
    • Primary Purpose: Treatment
    • Masking: None (Open Label)
  • Study Primary Completion Date: March 1, 2020

Detailed Description

A prospective study comparing the use of mini-autogenous skin grafts and skin homograft versus autogenous skin grafts for covering post burn wounds in children so that the patient can continue on his/her normal life early with less deformities

Interventions

  • Procedure: Mini autogenous skin graft
    • mini-autogenous skin grafts and skin homograft versus autogenous skin grafts for covering post burn wounds in children.

Arms, Groups and Cohorts

  • Active Comparator: Mini autogenous skin grafts
    • we take the autogenous skin graft from the same patient then cut it into small pieces then we spread it over the burn wound on one limb then cover these small pieces with homogenous skin graft taken from another person.
  • Active Comparator: Autogenous skin graft
    • we take the regular autogenous one piece skin graft from the same patient and cover the burn wound on the other limb then we make a comparison between both limbs

Clinical Trial Outcome Measures

Primary Measures

  • The major outcome is to specify if the regular single piece autogenous skin graft is better than the new technique that uses small pieces mini autogenous skin grafts for treatment of post burn wounds in children. or vice versa?
    • Time Frame: 2 years
    • the spread of the small pieced autogenous skin grafts that are covered with homogenous skin graft over post burn wounds in children may give better results than the regular single pieced autogenous skin graft

Participating in This Clinical Trial

Inclusion Criteria

  • This study will include children (3-12) years old with (10-30) % body surface area burns, admitted to Assuit university hospital burn unit. – The raw areas in both upper and lower limbs will be the site of the study. Exclusion Criteria:

  • Patients younger than 3 years old. – Patients with burns more than 30% of total body surface area. – Patients with medical or mental diseases.

Gender Eligibility: All

Minimum Age: 3 Years

Maximum Age: 12 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Assiut University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Mohamed Salah El Din Mohamed Hassan, Resident doctor – Assiut University
  • Overall Official(s)
    • Mohamed St Salah El Din, Resident, Study Chair, Doctor Mostafa El Sonbaty

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.