Clinical Audit on the Managment in Assiut University Children Hospital

Overview

clinical audit on the Managment of rheumatic fever in assiut university children hospital.

Full Title of Study: “Clinical Audit on the Managment of Rheumatic Fever in Assiut University Children Hospital”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: March 24, 2020

Detailed Description

Acute rheumatic fever,an auto immune response to Group A streptococcus infection of the upper respiratory tract,may result in carditis.when the inflammation leads to permenant damage of the valves the individual has rheumatic heart disease. Recurrences of rheumatic fever are likely in the absence of preventive measures and may cause further cardiac valve and muscle damage,leading to heart failure,stroke and premature death.bacterial endocarditis is also a complication.

Interventions

  • Diagnostic Test: C reactive protein, anti streptolysin o antibody test ,erythrocyte sedimentation rate
    • Throat culture to detect the causative organism

Clinical Trial Outcome Measures

Primary Measures

  • laboratory investigations (ASOt , ESR . CRP)
    • Time Frame: One year from October 2017 to september 2018
    • laboratory investigations that measure the inflammation process will be used and the target that the ASOt not increase 1/400

Secondary Measures

  • clinical measures
    • Time Frame: One year from October 2017 to september 2018
    • improvement of arthritis if found

Participating in This Clinical Trial

Inclusion Criteria

  • patients with confirmed diagnosis of rheumatic fever based on laboratory investigations. Exclusion Criteria:

  • No

Gender Eligibility: All

Minimum Age: 5 Years

Maximum Age: 15 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Assiut University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Patricia reda hanna, Resident doctor – Assiut University

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