Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes

Overview

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of type 2 diabetes (T2D) is heavily debated but evidence from large populations in China is scant. The investigators aim to use data from the China Health and Nutrition Survey (CHNS) to assess the long-term association between fish, PUFA intake and T2D risk.

Full Title of Study: “Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes in CHNS”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: December 31, 2011

Detailed Description

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of T2D is heavily debated but evidence from large populations in China is still lacking. The investigators aim to utilize data from China Health and Nutrition Survey (CHNS, 1997-2011). The investigators will calculate cumulative means of fish and PUFA intake based on 3-day food records in each wave. Sex-specific Cox regression models will be used to estimate relative risk of T2D. Results from this work will provide epidemiological evidence for improving recommendations on fish and PUFA intake for Chinese in dietary guidelines.

Clinical Trial Outcome Measures

Primary Measures

  • Type 2 diabetes
    • Time Frame: From entry into the study (baseline: 1997-2009) until 2011
    • Incidence of type 2 diabetes, on basis of self-reported physician diagnosis, fasting plasma glucose ≥ 7.0 mmol/l or HbA1c ≥ 6.5%

Secondary Measures

  • Fish and polyunsaturated fatty acids intake
    • Time Frame: From entry into the study (baseline: 1997-2009) until 2011
    • Cumulative averages of fish and PUFA intake based on 3-day 24-hr recall in each wave

Participating in This Clinical Trial

Inclusion Criteria

  • Adults aged ≥20 with complete data on diet and follow-up time Exclusion Criteria:

  • Missing information for Type 2 diabetes – Type 2 diabetes – Cardiovascular disease

Gender Eligibility: All

Minimum Age: 20 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Zhejiang University
  • Collaborator
    • National Institute of Health and Nutrition
  • Provider of Information About this Clinical Study
    • Principal Investigator: Jingjing Jiao, Associate Professor – Zhejiang University

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