Screening and Assessing the Risk Factors and Complications of Chronic Kidney Disease

Overview

The study is an observational, cross-sectional study aimed at screening and accessing risk factors and complications for Chinese chronic kidney disease (CKD) patients. To investigate the prevalence of hypertension, cardiovascular and cerebrovascular diseases, protein energy malnutrition(PEM), cognitive impairment and other complications in the CKD patients. To develop biomarkers of CKD.

Full Title of Study: “Screening and Assessing the Risk Factors and Complications of Chronic Kidney Disease:a Cross – Sectional Study”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: May 2018

Interventions

  • Other: blood sample collection
    • blood sample collection

Clinical Trial Outcome Measures

Primary Measures

  • Prevalence of CKD complications
    • Time Frame: baseline
    • hypertension, cardiovascular and cerebrovascular diseases, protein energy malnutrition(PEM), cognitive impairment
  • Biomarkers of kidney function
    • Time Frame: baseline

Secondary Measures

  • Genetic analyses
    • Time Frame: baseline
    • circulating microRNA
  • Questionnaire assessing cognitive function
    • Time Frame: baseline
    • Montreal Cognitive Assessment-Basic Chinese Version
  • Questionnaire assessing depression
    • Time Frame: baseline
    • Beck Depression Inventory scores
  • Questionnaire assessing risk of malnutrition
    • Time Frame: baseline
    • Malnutrition-Inflammation Score
  • Questionnaire assessing dietary intake
    • Time Frame: baseline
    • Food Frequency Questionnaire
  • Questionnaire assessing quality of life
    • Time Frame: baseline
    • Activity of daily living(ADL)and kidney disease quality of life (KDQOLTM-36)

Participating in This Clinical Trial

Inclusion Criteria

  • age≥18 years – clinical diagnosis of CKD – signed informed consent Exclusion Criteria:

  • End-stage renal disease(ESRD) or dialysis – Acute kidney injure(AKI) – history of solid organ or bone marrow transplantation – active malignancy within 24 months prior to screening or metastatic cancer – HIV infection or AIDS – acute inflammation

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Chinese PLA General Hospital
  • Provider of Information About this Clinical Study
    • Principal Investigator: Chen Xiangmei, Academician of Chinese Academy of Engineering – Chinese PLA General Hospital
  • Overall Official(s)
    • xiangmei chen, Principal Investigator, Chinese PLA General Hospital
  • Overall Contact(s)
    • guangyan cai, 00861066935462, caiguangyan@sina.com

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.