Fish, Polyunsaturated Fatty Acids Intake and Mortality
Overview
Data linking fish, polyunsaturated fatty acids intake and mortality are lacking and conflicting. We aim to use data from the China Health and Nutrition Survey (CHNS) and National Health and Nutrition Examination Survey (NHANES) to investigate the associations of fish and polyunsaturated fatty acids (PUFA) intake with mortality in Chinese and US populations. The study findings will be informative for addressing the role of fish and specific PUFA in human health and improve basis for dietary recommendations.
Full Title of Study: “Fish, Polyunsaturated Fatty Acids Intake and Mortality: Analysis of CHNS and NHANES”
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: December 2011
Detailed Description
Data from the China Health and Nutrition Survey (CHNS, from 1989 to 2011) and National Health and Nutrition Examination Survey (NHANES), including NHANES III conducted in 1988-1994 and continuous NHANES 1999-2010 were used to investigate the associations of fish and polyunsaturated fatty acids intake with mortality.The following variables were used: 1. Demographics: age, sex, race/ethnicity, residence 2. Socioeconomic variables: education, marital status, 3. Dietary variables: Intakes of fish, polyunsaturated fatty acids, total energy, vegetables, fruits, red meat and saturated fat 4. Clinical assessments: hypertension, diabetes, cancer, cardiovascular disease (CVD), family history of CVD
Clinical Trial Outcome Measures
Primary Measures
- Total Mortality
- Time Frame: From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years
- Total Mortality from All Causes
Secondary Measures
- Cause-specific mortality
- Time Frame: From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years
- Cause-specific mortality from diseases
Participating in This Clinical Trial
Inclusion Criteria
- Adults aged ≥20 with complete data on diet and follow-up time Exclusion Criteria:
- Missing information for mortality – Cardiovascular disease – Cancer
Gender Eligibility: All
Minimum Age: 20 Years
Maximum Age: N/A
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- Zhejiang University
- Collaborator
- National Institute of Health and Nutrition
- Provider of Information About this Clinical Study
- Principal Investigator: Jingjing Jiao, Associate Professor – Zhejiang University
Citations Reporting on Results
Zhao LG, Sun JW, Yang Y, Ma X, Wang YY, Xiang YB. Fish consumption and all-cause mortality: a meta-analysis of cohort studies. Eur J Clin Nutr. 2016 Feb;70(2):155-61. doi: 10.1038/ejcn.2015.72. Epub 2015 May 13.
Rizos EC, Ntzani EE, Bika E, Kostapanos MS, Elisaf MS. Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis. JAMA. 2012 Sep 12;308(10):1024-33. doi: 10.1001/2012.jama.11374.
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