Fish, Polyunsaturated Fatty Acids Intake and Mortality

Overview

Data linking fish, polyunsaturated fatty acids intake and mortality are lacking and conflicting. We aim to use data from the China Health and Nutrition Survey (CHNS) and National Health and Nutrition Examination Survey (NHANES) to investigate the associations of fish and polyunsaturated fatty acids (PUFA) intake with mortality in Chinese and US populations. The study findings will be informative for addressing the role of fish and specific PUFA in human health and improve basis for dietary recommendations.

Full Title of Study: “Fish, Polyunsaturated Fatty Acids Intake and Mortality: Analysis of CHNS and NHANES”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: December 2011

Detailed Description

Data from the China Health and Nutrition Survey (CHNS, from 1989 to 2011) and National Health and Nutrition Examination Survey (NHANES), including NHANES III conducted in 1988-1994 and continuous NHANES 1999-2010 were used to investigate the associations of fish and polyunsaturated fatty acids intake with mortality.The following variables were used: 1. Demographics: age, sex, race/ethnicity, residence 2. Socioeconomic variables: education, marital status, 3. Dietary variables: Intakes of fish, polyunsaturated fatty acids, total energy, vegetables, fruits, red meat and saturated fat 4. Clinical assessments: hypertension, diabetes, cancer, cardiovascular disease (CVD), family history of CVD

Clinical Trial Outcome Measures

Primary Measures

  • Total Mortality
    • Time Frame: From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years
    • Total Mortality from All Causes

Secondary Measures

  • Cause-specific mortality
    • Time Frame: From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years
    • Cause-specific mortality from diseases

Participating in This Clinical Trial

Inclusion Criteria

  • Adults aged ≥20 with complete data on diet and follow-up time Exclusion Criteria:

  • Missing information for mortality – Cardiovascular disease – Cancer

Gender Eligibility: All

Minimum Age: 20 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Zhejiang University
  • Collaborator
    • National Institute of Health and Nutrition
  • Provider of Information About this Clinical Study
    • Principal Investigator: Jingjing Jiao, Associate Professor – Zhejiang University

Citations Reporting on Results

Zhao LG, Sun JW, Yang Y, Ma X, Wang YY, Xiang YB. Fish consumption and all-cause mortality: a meta-analysis of cohort studies. Eur J Clin Nutr. 2016 Feb;70(2):155-61. doi: 10.1038/ejcn.2015.72. Epub 2015 May 13.

Rizos EC, Ntzani EE, Bika E, Kostapanos MS, Elisaf MS. Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis. JAMA. 2012 Sep 12;308(10):1024-33. doi: 10.1001/2012.jama.11374.

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.