Comparison of Three Techniques for Analgesia After Abdominoplasty

Overview

This study was conducted to demonstrate post-abdominoplasty analgesic duration consequent to three different surgically infiltrated LA techniques; bilateral TAPB, bilateral RSB and subcutaneous infiltration using the same volume of 0.25% bupivacaine (40 ml). Pain score, total analgesic rescue requests and the total amount of systemic rescue analgesia used in the first postoperative day in addition to any detected postoperative complications were also recorded.

Full Title of Study: “The Efficacy of Three Different Surgically Infiltrated Local Anesthetic Techniques in Abdominoplasty”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Prevention
    • Masking: Single (Outcomes Assessor)
  • Study Primary Completion Date: June 5, 2017

Interventions

  • Drug: Transevrsus abdominus plane block
    • a blunt needle was advanced in the midaxillary line to reach the fascial layer between the internal oblique and transverse abdominis muscles detected by facial click sensation. The LA was slowly injected so as to detect any sign of toxicity or incorrect needle tip position (as resistance) requiring needle repositioning then TAPB was repeated on the opposite side.
  • Drug: Rectus sheath block
    • In RSB group, 2-3 cm from midline, about 3-5 cm above the umbilicus, the needle was advanced at right angle to the skin. The needle reaches the space between the posterior layer of the rectus sheath and rectus abdominis muscle detected by firm resistance of the posterior wall, The LA was slowly injected then the same steps were repeated on the other side.
  • Drug: local anesthesia infiltartion
    • 40 mls of 0.255 bupivacaine will be infiltrated at skin incision

Arms, Groups and Cohorts

  • Active Comparator: Transevrsus abdominus plane block group
  • Active Comparator: Rectus sheath block group
  • Active Comparator: local infiltration group

Clinical Trial Outcome Measures

Primary Measures

  • morphine consumption (mg)
    • Time Frame: up to 24 hours
    • postoperative morphine consumption in milligrams in the 1st 24 hours postoperatively

Participating in This Clinical Trial

Inclusion Criteria

  • all patients listed for abdominoplasty Exclusion Criteria:

  • allergy to bupivacaine

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 50 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Mansoura University
  • Provider of Information About this Clinical Study
    • Principal Investigator: AlRefaey Kandeel, lecturer – Mansoura University

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