Super Chinese Nephrotic Syndrome Registration System (SUCCESS)

Overview

The investigators are registering all nephrotic syndrome (NS) patients regardless of the primary causes and developing a NS database in China. Patients will be followed-up and both baseline and follow-up information will be recorded in the registration system. The treatment response, longitudinal changes of renal function, renal survival, patient survival, infection events and acute kidney injury etc, will be analyzed using the NS database.

Study Type

  • Study Type: Observational [Patient Registry]
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: December 2026

Detailed Description

The investigators are registering all NS patients regardless of the primary causes in China. Patients' demographic characteristics (including age, gender, height, weight, BMI, smoking, drinking, and education), clinical characteristics (including systolic blood pressure, diastolic blood pressure, primary cause of NS, and lab measurements of serum, urine), pathological characteristics, treatment and treatment response, complications and outcomes. Patients will be followed up, the demographic, clinical characteristics, treatment, lab tests of blood and urine and complications of patients will be collected and recorded at each visit. The investigators also record the outcome at each visit, such as treatment response, longitudinal changes of renal function, hospitalization, occurrence of infection or cardiovascular events etc. The outcomes will be analyzed using the NS database.

Interventions

  • Other: No intervention
    • Registration of all NS patients in the First Affiliated Hospital of Sun Yat-sen University and other hospitals which have signed the contract in China.

Arms, Groups and Cohorts

  • Nephrotic syndrome patients
    • Patients diagnosis as nephrotic syndrome (NS)

Clinical Trial Outcome Measures

Primary Measures

  • The patient survival in NS patients
    • Time Frame: 10 years

Secondary Measures

  • Renal survival in NS patients
    • Time Frame: 10 years
    • Renal survival including end stage renal disease, dialysis, renal transplantation
  • Longitudinal changes of renal function of NS patients
    • Time Frame: 10 years
  • Treatment response of NS patients
    • Time Frame: 10 years
  • Infection rate of NS patients
    • Time Frame: 10 years

Participating in This Clinical Trial

Inclusion Criteria

  • Nephrotic syndrome patients regardless of the primary causes Exclusion Criteria:

  • No

Gender Eligibility: All

Minimum Age: 14 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Sun Yat-sen University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Xue Qing Yu, Professor – Sun Yat-sen University
  • Overall Contact(s)
    • Xueqing Yu, M.D. & Ph.D, yuxq@mail.sysu.edu.cn

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