Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City

Overview

The research question is "Are the different types of house in Ho Chi Minh city equally contributing to chronic respiratory diseases?". According to this question, a cross-sectional and explorative study was set up to explore the differences in the environmental characteristics and prevalence of chronic respiratory diseases among common housing types in Ho Chi Minh city. Preliminary work was performed in 100 houses (20 houses per type, included tube houses, rental houses, rural houses, slum and apartment) from November 2013 to June 2015. It included measures by environmental devices, questionnaires and indoor activities diaries. This study will aim to collect information about the prevalence of chronic respiratory diseases (CRDs) inside those house types to understand more about role of house types in developing CRDs. The objective is: 1. to evaluate the relationships between the type of house and lung function of inhabitants in each housing type. 2. to evaluate the effects of environmental risk factors in each house type on prevalence of CRDs

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Non-Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Screening
    • Masking: None (Open Label)
  • Study Primary Completion Date: July 2017

Interventions

  • Other: Questionnaire
  • Device: Lung function test
    • Basic lung function test performed with a micro-spirometer, without broncho dilatator

Arms, Groups and Cohorts

  • Experimental: Tube houses
    • Tube Houses. Group of 75-100 houses, with 4 inhabitants per house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
  • Experimental: Apartment
    • Apartments. Group of 75-100 apartments, with 4 inhabitants per apartment. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
  • Experimental: Rental Houses
    • Rental Houses. Group of 150-200 rental houses, with 2 inhabitants per rental house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
  • Experimental: Rural houses
    • Rural Houses. Group of 40-60 rural houses, with 5 inhabitant per rural house. Expected number of participants: 200-300. Predicted number of non-smoker chronic respiratory disease of 12-18.

Clinical Trial Outcome Measures

Primary Measures

  • FEV1/FVC
    • Time Frame: 5 minutes
    • Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test. FEV1: forced expiratory volume in one second. FVC: Forced vital capacity.
  • FVC
    • Time Frame: 5 minutes
    • Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test.FVC: Forced vital capacity.
  • VC
    • Time Frame: 5 minutes
    • Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes performed during the same test. VC: Vital capacity
  • FEF 25-75%
    • Time Frame: 5 minutes
    • Basic lung function test, without broncho dilatation (micro-spirometer).All lung function related outcomes are performed during the same test. FEF: Forced expiratory flow
  • Socio-demographic status
    • Time Frame: around 10 minutes
    • Socio-demographic data, assessed by a home made questionnaire
  • Health status
    • Time Frame: around 10 minutes
    • Health status (symptomatology) data, assessed by a home made questionnaire
  • Indoor air exposure time
    • Time Frame: around 10 minutes
    • Indoor air exposure (time spent indoor within housing types, with associated air characteristics) data, assessed by a home made questionnaire

Participating in This Clinical Trial

Inclusion Criteria

  • Everybody Exclusion Criteria:

  • Not able to answer the questionnaire or give informed consent – Have a contra-indication for lung function test (acute myocardial infarction less that 1 month ago, pain related to spirometry, dementia/confused)

Gender Eligibility: All

Minimum Age: 10 Years

Maximum Age: 65 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Brugmann University Hospital
  • Provider of Information About this Clinical Study
    • Principal Investigator: Olivier Michel, Head of clinic – Brugmann University Hospital

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