Caffeine Intake and Additive Effects on Cognition
Overview
Caffeine is a methylxanthine commonly consumed by the population for their psychostimulant properties, and their intake when in moderate doses seem to produce positive effects on stress, mood and memory. So, understanding that a positive effect of aerobic exercise can be displayed also on cognition, as caffeine, when in proper proportions, the investigators do not know if the joining of the two strategies into a single activity would be able to promote additional effects enhancing cognitive processes related to memory, attention, and motor reaction time.
Full Title of Study: “Can Caffeine Intake Combined With Aerobic Exercise Leads to Cognitive Improvement and Psychomotor Performance in Trained Individuals?”
Study Type
- Study Type: Interventional
- Study Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Study Primary Completion Date: November 2015
Detailed Description
Determine if 500 mg of caffeine can generate additional effects to 30 minutes of aerobic exercise enhancing cognitive memory tasks (Rey Auditory Verbal Learning Test – RAVLT), attention (sustained attention span; working speed; Percentual of errors by confusion) and simple reaction time (SRT).
Interventions
- Other: Caffeine Intake
- The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.
- Other: Placebo Intake
- The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.
Arms, Groups and Cohorts
- Experimental: Caffeine Intake
- The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.
- Placebo Comparator: Placebo Intake
- The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.
Clinical Trial Outcome Measures
Primary Measures
- Simple Reaction Time
- Time Frame: Acute Change from Baseline Psychomotor test to 1 min after aerobic exercise, and after 30 min
- Rey Auditory Verbal Learning Test
- Time Frame: Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min
- Sustained Attention Test
- Time Frame: Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min
Participating in This Clinical Trial
Inclusion Criteria
- Fighting men – Low levels of consumption of caffeine daily Exclusion Criteria:
- Use more than 400 mg caffeine day – Mental diseases – Cognitive deficits
Gender Eligibility: Male
Minimum Age: 18 Years
Maximum Age: 45 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- Universidade Federal do Rio de Janeiro
- Provider of Information About this Clinical Study
- Principal Investigator: Alberto Souza de Sá Filho, Doctorade in Mental Health – Universidade Federal do Rio de Janeiro
- Overall Official(s)
- Sérgio Machado, PhD, Study Director, Salgado de Oliveira University
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