A Comparison of Colonic Bile Acid Content Following Right and Left Colectomies

Overview

The aim of this study is to evaluate whether there is a difference in the bile acid content in the bowel in patients after right versus left colectomy. There is compelling evidence that patients under going resection of the right colon versus left coolon have a lower polyp detection rate in surveillance colonoscopies. The investigators intend to evaluate feces of patients undergoing left and right colectomies; prior to their surgery and again three and six months aftet the surgery. The investigators plan to compare the content of the different bile acids and to compare the content between the two groups.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: January 2017

Clinical Trial Outcome Measures

Primary Measures

  • Colonic bile acid content
    • Time Frame: two years

Participating in This Clinical Trial

Inclusion Criteria

  • Age above 18. – Patients intended to undergo a colectomy for colonic cancer – Patients willing and participate and able to sign an informed consent Exclusion Criteria:
  • Age under 18. – Patients with Inflammatory Bowel Disease (Crohn's, Ulcerative colitis). – Patients refusing to participate or are unable to understand or sign an informed consent
  • Gender Eligibility: All

    Minimum Age: 18 Years

    Maximum Age: N/A

    Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

    Investigator Details

    • Lead Sponsor
      • Meir Medical Center
    • Provider of Information About this Clinical Study
      • Principal Investigator: Ilan Kent, Medical Doctor – Meir Medical Center

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