Impact of Treatment With Colistin on Mortality Bacteremia Multiresistant Acinetobacter Baumannii Sensitive Colistin in Patients Critical

Overview

The present study was designed to study the impact of empirical treatment with colistin empirical monotherapy and combined treatment with tigecycline and vancomycin on mortality of bacteremia Multiresistant Acinetobacter Baumannii . The main objective was to evaluate the efficacy of empirical treatment with colistin and combined targeted therapy. The different therapeutical interventions were administered following the routine clinical practice in the medical centre and the investigator did not assign specific interventions to the subjects of the study.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: December 2012

Interventions

  • Drug: Colistin
  • Drug: Tigecycline
  • Drug: Vancomycin

Clinical Trial Outcome Measures

Primary Measures

  • All-cause 30-day mortality (crude).
    • Time Frame: 30 days

Secondary Measures

  • All-cause 14 day mortality (crude).
    • Time Frame: 14 days

Participating in This Clinical Trial

Inclusion Criteria

  • Critics included patients ≥ 16 years with monomicrobial bloodstream infections by multiresistant acinetobacter baumannii to carbapenems and sensitive to colistin accompanied by systemic inflammatory response syndrome, provided they have received targeted treatment with colistin.

Gender Eligibility: All

Minimum Age: 16 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Maimónides Biomedical Research Institute of Córdoba
  • Provider of Information About this Clinical Study
    • Sponsor

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