Fibroscan Predicts Complications After Hepatectomy

Overview

Most of the postoperative complications that may occur after hepatectomy are related to the underlying liver background, and the common preoperative tests do not completely predict such complications. Transient elastography by Fibroscan is used to calculate the stiffness and the steatosis of the liver, and it may be also used to predict postoperative complications after hepatectomy

Full Title of Study: “Role of Fibroscan in Predicting Complications After Hepatectomy”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: October 2014

Detailed Description

A prospective cohort study on consecutive patients scheduled for hepatectomy was planned. Fibroscan was performed during the preoperative workup. Accuracy of the liver stiffness and steatosis measured by Fibroscan in predicting the presence of cirrhosis, of steatosis, and the development of postoperative complications was assessed by ROC curve, and multivariate analysis.

Clinical Trial Outcome Measures

Primary Measures

  • Accuracy of Fibroscan in predicting complication after hepatectomy
    • Time Frame: 90 days
    • Calculation of the accuracy of the liver stiffness and steatosis measured with the Fibroscan in predicting complications after hepatectomy. The values of the stiffness and steatosis will be correlated with the number of complications

Participating in This Clinical Trial

Inclusion Criteria

  • Patients with primary and secondary tumors scheduled for hepatectomy at our Unit – Written consent to get the Fibroscan during the preoperative workup Exclusion Criteria:

  • Refute to get the Fibroscan – Loss of data

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • University of Milan
  • Provider of Information About this Clinical Study
    • Principal Investigator: Prof. Guido Torzilli, Professor of Surgery – University of Milan
  • Overall Official(s)
    • Guido Torzilli, MD, PhD, Study Director, Humanitas Research Hospital

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