Estimated Glomerular Filtration Rate After Kidney Transplantation – the Formula MDRD, CKD-EPI or Cockroft-Gault?


The study included 300 patients who are post-kidney transplantation (> 3 months and <10 years). An analysis of body composition using bioelectrical impedance, calculated BMI and serum creatinine was determined. Glomerular filtration rate (GFR) was calculated using the formula CKD-EPI, Modification of Diet in Renal Disease (MDRD) and Cockroft-Gault.

Full Title of Study: “Estimated Glomerular Filtration Rate After Kidney Transplantation – the Formula Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) or Cockroft-Gault?”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: September 2015


  • Other: Estimating of formula MDRD, CKD-EPI, Cockroft-Gault,
  • Device: Tanita BC 418- Bioelectrical impedance analysis
    • The device measured the size of total body water (TBW), fat mass (FM%), visceral fat%, fat free mass (FFM), and basal metabolic rate (BMR) (kcal).

Arms, Groups and Cohorts

  • Patients After Kidney Transplantation
    • A total of 300 consecutive patients admitted to routine visit in Transplant Centre with functioning graft longer than 3 months to 10 years

Clinical Trial Outcome Measures

Primary Measures

  • Differences in estimating GFR using formula MDRD, CKD-EPI and Cockroft-Gault in short and long-term postoperative period.
    • Time Frame: 1 day

Participating in This Clinical Trial

Inclusion Criteria

  • give voluntary consent to participate in the study – functioning graft longer than 3 months to 10 years – no clinical cardiovascular disease during the 6 months preceding entry – stable graft function- glomerular filtration rate > 30 ml/min/1.73 m2, creatinine concentration <2.5 mg/dl Exclusion Criteria:

  • not meet the above criteria – episode of illness (for example: infection) – pregnancy

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Medical University of Warsaw
  • Provider of Information About this Clinical Study
    • Principal Investigator: Łukasz Czyżewski, Łukasz Czyżewski – Medical University of Warsaw

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