Assessment of Prokinetic Effects of Erythromycin in Emergency Patients With a Full Stomach
Overview
The aims of the study is to assess whether the intravenous infusion of 3 mg/kg erythromycin has a significant gastrokinetic effect leading to empty the stomach in less than 90 minutes in non-fasting patients undergoing emergency trauma surgery.
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: November 2014
Clinical Trial Outcome Measures
Primary Measures
- ultrasonographic measurement of antral area
- Time Frame: 30 minutes and immediately before erythromycin infusion, and 30, 60 and 90 min after the start of erythromycin infusion
Participating in This Clinical Trial
Inclusion Criteria
- Emergency surgery for trauma – ASA 1 and 2 patients – Full stomach (antral area > 550 mm²) – Adult patients Exclusion Criteria:
- No contraindication to erythromycin – Extreme emergency surgery (time frame < 90 min between arrival in the service and the start of the surgery) – gastroparesis or pathology associated with gastroparesis
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- Lionel Bouvet
- Provider of Information About this Clinical Study
- Sponsor-Investigator: Lionel Bouvet, MD PhD – Hôpital Edouard Herriot
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