Assessment of Prokinetic Effects of Erythromycin in Emergency Patients With a Full Stomach

Overview

The aims of the study is to assess whether the intravenous infusion of 3 mg/kg erythromycin has a significant gastrokinetic effect leading to empty the stomach in less than 90 minutes in non-fasting patients undergoing emergency trauma surgery.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: November 2014

Clinical Trial Outcome Measures

Primary Measures

  • ultrasonographic measurement of antral area
    • Time Frame: 30 minutes and immediately before erythromycin infusion, and 30, 60 and 90 min after the start of erythromycin infusion

Participating in This Clinical Trial

Inclusion Criteria

  • Emergency surgery for trauma – ASA 1 and 2 patients – Full stomach (antral area > 550 mm²) – Adult patients Exclusion Criteria:

  • No contraindication to erythromycin – Extreme emergency surgery (time frame < 90 min between arrival in the service and the start of the surgery) – gastroparesis or pathology associated with gastroparesis

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Lionel Bouvet
  • Provider of Information About this Clinical Study
    • Sponsor-Investigator: Lionel Bouvet, MD PhD – Hôpital Edouard Herriot

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