Downhill Walking Training in COPD
Overview
This randomized control trial will investigate whether a modality that generates more contractile muscle fatigue with lower ventilatory requirements render better results after a 12-week exercise training program in subjects with COPD. Subjects will be randomized to either exercise in a training program including downhill walking or to exercise in a training program including conventional walking.
Full Title of Study: “Downhill Walking to Enhance Training Effects in Patients With COPD”
Study Type
- Study Type: Interventional
- Study Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Primary Purpose: Treatment
- Masking: None (Open Label)
- Study Primary Completion Date: April 2015
Interventions
- Other: Downhill walking training
- Walk on a treadmill with a negative inclination.
- Other: Conventional walking training
- Walk on a treadmill without inclination. Possible to progress training intensity with positive inclinations
Arms, Groups and Cohorts
- Experimental: Downhill walking training
- Exercise training including treadmill walking with a negative inclination.
- Active Comparator: Conventional walking training
- Exercise training including treadmill walking without inclination. Possible to progress training intensity with positive inclinations.
Clinical Trial Outcome Measures
Primary Measures
- changes in 6-minute walking distance
- Time Frame: changes from baseline to Week 12
Participating in This Clinical Trial
Inclusion Criteria
- Patients with a primary diagnosis of COPD according to internationally accepted guidelines – Patients referred to the outpatient PR program of Gasthuisberg University Hospital(Leuven, Belgium) Exclusion Criteria:
- Any underlying disease or musculoskeletal limitation that could impair the ability to perform any of the exercise training modalities – Absence of exacerbations in the previous month before entering the present study – Patients included on the waiting list for lung transplantation
Gender Eligibility: All
Minimum Age: N/A
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- KU Leuven
- Collaborator
- Research Foundation Flanders
- Provider of Information About this Clinical Study
- Principal Investigator: Thierry Troosters, Prof. – KU Leuven
- Overall Official(s)
- Thierry Troosters, PhD, Principal Investigator, KU Leuven
- Overall Contact(s)
- Thierry Troosters, PhD, Thierry.Troosters@kuleuven.be
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