Does Muscle Wasting Always Mean Muscle Weakness? A Prevalence Study in COPD


Peripheral muscle mass and strength are relevant indicators of COPD survival. Current guidelines recommend to assess muscle strength only in muscle wasted patients. However, a recent study reported quadriceps weakness without muscle wasting (Menon, M et al. Resp. Res.2012, 13:119). Thus, these guidelines raise the risk to miss out some weak patients. In clinical settings, fat-free-mass index (FFMI) is indicated as a simple index to assess muscle wasting. We aimed at determining the prevalence of patients entering in pulmonary rehabilitation (PR) a priori not eligible for muscle strength evaluation given the lack of muscle wasting clinical signs.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: March 2014

Clinical Trial Outcome Measures

Primary Measures

  • Muscle wasting in COPD patient
    • Time Frame: baseline

Secondary Measures

  • Muscle weakness in COPD patient
    • Time Frame: baseline

Participating in This Clinical Trial

Inclusion Criteria

  • Patients who have got FFMI (bioimpedance) – Patients who have done quadriceps muscle strenght evaluation Exclusion Criteria:

  • Patients without FFMI – Patients without quadriceps muscle strenght

Gender Eligibility: All

Minimum Age: N/A

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • 5 Santé
  • Provider of Information About this Clinical Study
    • Sponsor

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