Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment
Overview
This study investigates the benefit of using chlorhexidine gel as an antimicrobial agent in orthodontic patient to reduce caries risk and the possible consequential effect of this use on the orthodontic brackets used for the treatment. The investigators hypothesis is that chlorhexidine gel use can reduce caries risk in orthodontic patients with out causing damage to the bonded ceramic or metal orthodontic brackets.
Full Title of Study: “Effect of Chlorhexidine Gel on Bacterial Count and Orthodontic Brackets During Fixed Orthodontic Treatment; In-vivo & In-vitro Study”
Study Type
- Study Type: Interventional
- Study Design
- Allocation: N/A
- Intervention Model: Single Group Assignment
- Primary Purpose: Prevention
- Masking: None (Open Label)
- Study Primary Completion Date: April 2014
Interventions
- Drug: Chlorhexidine gluconate
Arms, Groups and Cohorts
- Experimental: chlorhexidine gel
- anti microbial agent that prevents the formation of plaque and reduces caries risk
Clinical Trial Outcome Measures
Primary Measures
- mutants streptococcus count
- Time Frame: 48 hours
- measures the change in bacterial count before and after application of the gel
Secondary Measures
- friction
- Time Frame: 2 minutes
- measures static and dynamic friction in Newton
Participating in This Clinical Trial
Inclusion Criteria
- Patients' age range from 18-30 years. – Fixed orthodontic treatment. – All the patients are at the end of leveling and alignment stage. – Initial bacterial count indicates high caries risk. – All patients will be given good oral hygiene instruction at the first visit. – The subjects had not taken antibiotics for at least 6 weeks before saliva sampling or during the experimental period. – All subjects used a fluoride dentifrice twice a day. Exclusion Criteria:
- Patients' age more or less then the age range specified. – Removable orthodontic treatment. – Patients at early stages of leveling and alignment. – Initial bacterial count indicates low caries risk. – Subjects that have taken antibiotics for at least 6 weeks before saliva sampling.
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 30 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- King Abdulaziz University
- Provider of Information About this Clinical Study
- Principal Investigator: Dr. Samar Al-Bazi, Doctor – King Abdulaziz University
- Overall Official(s)
- Samar M Al-Bazi, Principal Investigator, King Abdulaziz University
- Overall Contact(s)
- Mona A Abbassy, 0096658349507, monaabbassy@gmail.com
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