Nutritional Status Among naïve HIV Infected Patients and HIV Infected Patients Receiving Highly Active Antiretroviral Therapy

Overview

A prospective cross-sectional study evaluates nutritional status and its relationship to the related factors in Thai HIV-infected patients who attending in out patient clinic.

Full Title of Study: “Nutritional Status Among naïve HIV-infected Patients and HIV-infected Patients Receiving Highly Active Antiretroviral Therapy”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: December 2010

Detailed Description

A prospective cross-sectional study evaluates nutritional status and its relationship to the related factors in Thai HIV-infected patients who attending in out patient clinic at The Thai Red Cross AIDS Research Centre, Bamrasnaradura Infectious Disease Institute, Surat Thani hospital, Khonkaen hospital, Sanpathong hospital and the Queen Savang Vadhana Hospital at Sri Racha . General Objective: To determine nutritional status among Thai People Living with HIV (PLHIV). Specific Objective: 1. To assess nutritional problems including undernutrition, overnutrition and others such as lipodystrophy, dyslipidemia, hyperglycemia, cardiovascular disease, etc. among naïve HIV-infected patients and HIV-infected patients undergoing HARRT by using ABCDEF approach: Anthropometric, Biochemical, Clinical, Dietary, Exercise and Family assessment. 2. To describe the relationship between the nutritional status and HIV disease staging and other related factors among naïve HIV-infected patients and HIV-infected patients undergoing HARRT. 3. To describe the prevalence of CVD and its relationship to cardiac risk factors 4. To validate the community screening tool developed by the Thai Nutrition Taskforce in HIV (TNT-HIV) by assessing the correlation of this tool and nutritional status.

Arms, Groups and Cohorts

  • Survey
    • Thai naive HIV-infected patients Thai HIV-infected patient reciering highly active antiretroviral therapy

Clinical Trial Outcome Measures

Primary Measures

  • Nutritional status and Nutritional situation
    • Time Frame: 1 year
    • Nutritional status and Nutritional situation in Naïve HIV infected patients and HIV-infected patients undergoing HAART. It will be collected by using ABCDEF approch: Anthropometric, Biochemistry, Clinical, Dietary, Exercise and Family assesment.

Secondary Measures

  • The prevalence of metabolic syndrome
    • Time Frame: 1 year
    • The prevalence of metabolic syndrome in Naïve HIV infected patients and HIV-infected patients undergoing HARRT using American Heart Association (AHA) and National Heart Lung and Blood Institute (NHLBI) criteria

Participating in This Clinical Trial

Inclusion Criteria

  • HIV positive – 18 years of age or older – Receiving ongoing care as part of the anonymous clinic, TRCARC, the antiretroviral therapy clinics at Bamrasnaradura Infectious Disease Institute, Surat Thani hospital, Khonkaen hospital, Sanpathong hospital and the Queen Savang Vadhana Hospital at Sri Racha. – Either naïve HIV-infected patients and HIV-infected patients undergoing HARRT Exclusion Criteria:

  • HIV negative – Patient who had active AIDS-related disorders within three months before participate the study – Patients who are pregnant

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Thai Red Cross AIDS Research Centre
  • Collaborator
    • World Health Organization
  • Provider of Information About this Clinical Study
    • Principal Investigator: Nittaya Phanuphak, M.D., Dr. – Thai Red Cross AIDS Research Centre
  • Overall Official(s)
    • Dr. Wisit Prasithsirikul, Principal Investigator, Bamrasnaradura Infectious Disease Institute

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.