Investigating Variation in Hospital Acute Coronary Syndrome Outcomes

Overview

To investigate the causes of hospital variation in outcomes from acute coronary syndromes in England and develop recommendations for improving patient care.

Full Title of Study: “Evaluation of the Methods and Management of Acute Coronary Events: 3. Investigating Variation in Hospital Acute Coronary Syndrome Outcomes”

Study Type

  • Study Type: Observational [Patient Registry]
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: February 2013

Detailed Description

Over the last few years the chance of dying from a heart attack in England and Wales has reduced dramatically. Even so, there remain huge differences in mortality between hospitals. For example, up to a third of patients with a heart attack who attend hospitals in England are more likely to die than would be expected. That is, the type of treatment and the risk of death depends upon where a patient lives and which hospital they attend. In part, the variation in death may be due to the services available at the hospital or to factors such as socioeconomic deprivation. It may also relate to other factors such as depression, cardiac rehabilitation and whether patients take their medication after discharge from hospital. Using powerful statistical approaches that include measures of quality of life, we propose to examine data about heart attacks in England and investigate the 'postcode lottery of care'. Our aim, using regional data about heart attacks is to identify and measure the effects of hospital care. This research will identify hospital qualities that promote improved patient care. In doing so, best practice will be highlighted and healthcare policy changed so that all patients will have an equal chance of surviving a heart attack.

Arms, Groups and Cohorts

  • Acute myocardial infarction
    • patient with suspected acute coronary syndrome (ACS).

Clinical Trial Outcome Measures

Primary Measures

  • delays to treatment
    • Time Frame: 12 months
    • Quantification of hospital attributable effects relating to early and late mortality

Secondary Measures

  • Describing trajectories of quality of life recovery patterns
    • Time Frame: 12 month
    • Describing trajectories of quality of life recovery patterns

Participating in This Clinical Trial

Inclusion Criteria

  • Age > 18 years – Both sexes – Acute admission to the acute Trust with suspected acute coronary syndrome Exclusion Criteria:

  • Patients at a terminal stage of any illness – Those in whom follow up would be inappropriate or impractical

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • University of Leeds
  • Provider of Information About this Clinical Study
    • Principal Investigator: Oras Alabas, Dr – University of Leeds
  • Overall Official(s)
    • Chris P Gale, PhD, Principal Investigator, University of Leeds

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