Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis

Overview

One useful effect of early intravitreal corticotherapy is to diminish inflammatory complications after endophthalmitis, which may cause, at least in part, serious complications (retinal detachment, macular edema) which are, more than the infection, causes of the complications seen after acute endophthalmitis.

Full Title of Study: “Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis.”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: Single (Participant)
  • Study Primary Completion Date: October 2014

Interventions

  • Procedure: Intravitreal injection of Betamethasone + antibiotics
  • Procedure: Intravitreal injection of antibiotics

Arms, Groups and Cohorts

  • Experimental: with corticoids
  • Other: without corticoids

Clinical Trial Outcome Measures

Primary Measures

  • Measure the evolution of visual acuity
    • Time Frame: up to12 months

Participating in This Clinical Trial

Inclusion Criteria

  • All patients male or female with no age limit – Hospitalized for the diagnosis and treatment of acute endophthalmitis following cataract surgery – Who had given their consent after being informed about intravitreal corticotherapy Exclusion Criteria:

  • Patients who refused or were unable to give their consent – Prior intravitreal corticotherapy

Gender Eligibility: All

Minimum Age: N/A

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Centre Hospitalier Universitaire Dijon
  • Provider of Information About this Clinical Study
    • Sponsor

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