Effects of Sea Buckthorn Oil on Mucous Membranes


Aim of this study is to investigate the effects of intake of sea buckthorn oil on mucous membranes

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Basic Science
    • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Study Primary Completion Date: April 2013


  • Dietary Supplement: Sea buckthorn oil
  • Dietary Supplement: Placebo oil

Arms, Groups and Cohorts

  • Experimental: Sea buckthorn oil
    • 3 g (6 capsules)/day for three months
  • Placebo Comparator: Placebo oil
    • 3 g (6 capsules)/day for three months

Clinical Trial Outcome Measures

Primary Measures

  • Change from baseline in dryness related symptoms of genital mucous membranes
    • Time Frame: Interviews at baseline, at 2 months, at 3 moths (end of intervention), and daily during the study (symptom logbooks)
    • Interview for symptom score at baseline and study visits and a daily symptom logbook during the intervention

Secondary Measures

  • Change from baseline in vaginal pH
    • Time Frame: At baseline, at 3 months (end of intervention)

Participating in This Clinical Trial

Inclusion Criteria

  • women experiencing vaginal dryness – 55-75 years of age – at least 12 months from menstruation Exclusion Criteria:

  • use of estrogen replacement therapy

Gender Eligibility: Female

Minimum Age: 55 Years

Maximum Age: 75 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Aromtech Ltd.
  • Collaborator
    • The Finnish Funding Agency for Technology and Innovation
  • Provider of Information About this Clinical Study
    • Principal Investigator: Petra Larmo, R&D manager, Ph.D. – Aromtech Ltd.
  • Overall Official(s)
    • Risto Erkkola, Professor, Principal Investigator, Turun Gynekologikeskus, Turku, Finland

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