VEGF Gene Association With Response to Neovascular Age-related Macular Degeneration With Anti-VEGF Agents
Overview
The main purpose of this study is to investigate the association between VEGF gene polymorphism and the response to intravitreal drugs in neovascular age-related macular degeneration. This is a retrospective review of patients treated between 2008 and 2012 at the Institute of Vision, in Belo Horizonte, Brazil.
Full Title of Study: “VEGF Gene Polymorphism and Response to Intravitreal Anti-VEGF Agents in Neovascular Age-related Macular Degeneration”
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Retrospective
Participating in This Clinical Trial
Inclusion Criteria
- Diagnosis of neovascular age-related macular degeneration – Visual acuity better than 20/400 – Loading dose with three intravitreal injections of anti-VEGF agents, administred one per month over three months – Follow-up period of at least six months Exclusion Criteria:
- Choroidal neovascularization secondary to any other cause than age-related macular degeneration – Eyes with polypoidal choroidal vasculopathy – Eyes previously submitted to posterior vitrectomy – Other diseases that could affect visual acuity
Gender Eligibility: All
Minimum Age: 50 Years
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- Institute of Vision, Brasil
- Provider of Information About this Clinical Study
- Sponsor
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