Berlin Beat of Running Study

Overview

This prospective observational study will investigate the frequency of new onset atrial fibrillation (AF) and of further cardiac arrhythmias as well as of (clinically silent) cerebral lesions in endurance runners before, during and after the BMW-Berlin Marathon 2011.

Full Title of Study: “Berlin Beat of Running Study – Frequency of Cardiac Arrhythmias & Cerebral Lesions in Marathon Runners”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: September 2012

Detailed Description

Up to 120 experienced marathon runners will participate in the "Berlin Beat of Running Study" and will wear a transportable electrocardiogram (ECG) recorder at least 24 hours before, during and 24 hours after the BMW-Berlin Marathon. All participants will undergo brain MRI examinations to detect cerebral lesions within days before and after the marathon race, respectively. Moreover, serial blood samples will be taken a few days before, immediately after as well as a few days after the BMW-Berlin Marathon.

Clinical Trial Outcome Measures

Primary Measures

  • Rate of cardiac arrhythmias in marathon runners detected by mobile ECG-recording
    • Time Frame: Up to 48 hours after the marathon race.
    • During ECG recording

Secondary Measures

  • Rate of (clinically silent) cerebral lesions detected by 3 Tesla brain MRI.
    • Time Frame: 3 days
    • Up to 3 days after marathon.

Participating in This Clinical Trial

Inclusion Criteria

  • Age 35-65 years – at least 2 marathon runs within the last 5 years – weekly running of at least 40 km Exclusion Criteria:

  • Known cardiac arrhythmia or prior stroke – contraindication for MRI.

Gender Eligibility: All

Minimum Age: 35 Years

Maximum Age: 65 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Charite University, Berlin, Germany
  • Collaborator
    • Center for Stroke Research Berlin
  • Provider of Information About this Clinical Study
    • Principal Investigator: Karl Georg Haeusler, MD – Charite University, Berlin, Germany
  • Overall Official(s)
    • Karl Georg Haeusler, MD, Principal Investigator, Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin, Germany.
    • Matthias Endres, MD, Study Chair, Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin, Germany
    • Wilhelm Haverkamp, MD, Study Chair, Departement of Cardiology, Campus Virchow, Charité – Universitätsmedizin Berlin, Germany
    • Matthias Kruell, MD, Study Chair, Medical Institute BMW-Berlin Marathon
    • Peter U Heuschmann, MD, Study Chair, Center for Stroke Research Berlin
    • Gerhard Jan Jungehuelsing, MD, Principal Investigator, Center for Stroke Research Berlin

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.