Effects of Vibration Training on Exercise Capacity in COPD-patients

Overview

The aim of this study is to investigate the exercise capacity in COPD-patients performing a vibration training additional to a standard three-week rehabilitation program in comparison to patients performing merely a rehabilitation program.

Full Title of Study: “Effects of Vibration Training During a Three-week Rehabilitation on Exercise Capacity in Chronic Obstructive Pulmonary Disease (COPD) III/IV-Patients”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: None (Open Label)
  • Study Primary Completion Date: April 2011

Interventions

  • Other: whole body vibration training
    • performing squats for 3×3 minutes while using vibration platform three times a week

Arms, Groups and Cohorts

  • Experimental: Rehabilitation with vibration training
  • No Intervention: Rehabilitation without vibration training

Clinical Trial Outcome Measures

Primary Measures

  • 6-Minute-Walking-Distance
    • Time Frame: day 1, day 19
    • Change in 6-minute-walking-distance from baseline to day 19

Secondary Measures

  • Body Composition
    • Time Frame: day 1 and 19
    • Change in body composition from baseline to day 19
  • Isometric Maximum Handgrip Force
    • Time Frame: day 1, day 19
    • change in isometric max. handgrip force from baseline to day 19
  • BODE-Score
    • Time Frame: day 1, day 19
    • Change in Bode-Score from baseline to day 19
  • Lung Function
    • Time Frame: day 1
  • Arterial Blood Gas
    • Time Frame: day 1
  • Brain Natruretic Peptide (BNP)
    • Time Frame: day 1, day 19
    • change in BNP from baseline to day 19

Participating in This Clinical Trial

Inclusion Criteria

  • Chronic obstructive pulmonary disease III/IV Exclusion Criteria:

  • Severe exacerbations in the last 4 weeks prior to begin of study (definition of exacerbation: symptoms on more than 3 days with a relevant change in drug therapy (cortisone, antibiotics)) – Severe disease other than COPD, that could influence the results of the study – Abuse of alcohol or drugs – Simultaneously participation in another study – Tachypnea (>30/min) – Severe exacerbation during rehabilitation – Cardiac insufficiency (NYHA IV) – Myocardial infarction during the last 6 weeks – Mental-health problem – Pregnancy – Known HIV-infection – Slipped disk – Acute discopathy – Acute thrombosis – Implants in trained regions of the body (lower extremities) – Acute inflammation of the locomotor system, active arthrosis or rheumatoid arthritis – Acute tendinopathy in trained regions of the body – Acute hernia – Fresh fractures, wounds or scars in trained regions of the body – Gallstones or stones in the urinary tract collection system

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 75 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Schön Klinik Berchtesgadener Land
  • Provider of Information About this Clinical Study
    • Principal Investigator: Klaus Kenn, MD – Schön Klinik Berchtesgadener Land

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.