Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity
Near infrared spectroscopy (NIRS) provides a non-invasive means of continuously monitoring tissue oxygenation, which may be useful for diagnosis of acute compartment syndrome (ACS). Placement of these sensor pads on the surface of the skin must be such that light penetrates the intended compartment without inadvertently obtaining measurements of an adjacent compartment. The objective of this study is to examine whether the NIRS measurements of each compartment truly represent the tissue perfusion of the intended compartment, as indicated by the predictable decrease in muscle oxygenation of a given compartment in response to muscle fatigue. The investigators hypothesize that the tissue oxygenation values of the stimulated compartment will significantly decrease following muscle stimulation, indicating that the intended muscle compartment was successfully isolated. Additionally, the investigators hypothesize that NIRS values of unstimulated muscle compartments will not change from baseline.
- Study Type: Observational
- Study Design
- Time Perspective: Cross-Sectional
- Study Primary Completion Date: December 2016
- Behavioral: Muscle contraction
- Participants will perform a 30-60 second exercise designed to cause a temporary decrease in muscle oxygenation of a specific muscle group.
Arms, Groups and Cohorts
- NIRS values of all participants will be measured at baseline and following each 30-60 second exercise.
Clinical Trial Outcome Measures
- Near infrared spectroscopy
- Time Frame: <30 minutes
- NIRS values will be measured before and after muscle fatigue
Participating in This Clinical Trial
- 18-75 years old – no current extremity injuries – willing to provide written informed consent Exclusion Criteria:
- history of any anatomy-altering surgery to the extremity in question – history of peripheral vascular disease – history of pulmonary disease
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 75 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
- Lead Sponsor
- J&M Shuler
- Provider of Information About this Clinical Study
- Overall Official(s)
- Michael Shuler, MD, Principal Investigator, Athens Orthopedic Clinic, PA
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