Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)

Overview

A computerised neuropsychological test battery to be used as a standardised tool assessing the cognitive domains affected by idiopathic normal pressure hydrocephalus INPH was developed. The aim of this study is to investigate the reliability, validity and feasibility of the battery.

Full Title of Study: “Evaluation of a Computerised Neuropsychological Test Battery for Idiopathic Normal Pressure Hydrocephalus (INPH)”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: April 2010

Interventions

  • Device: Computerized neuropsychological test
    • Computerized neuropsychological test battery.
  • Other: Conventional neuropsychological test
    • Conventional neuropsychological test (paper and pen)

Arms, Groups and Cohorts

  • Test-retest
    • Forty-four healthy elderly 60-82 years old
  • Validity
    • Twenty six patients with various diseases and various ages
  • Feasibility
    • Twenty seven patients under the preoperative investigation for INPH

Clinical Trial Outcome Measures

Primary Measures

  • Validity
    • Time Frame: Within 24 h
    • Computerized test battery and equivalent standard neuropsychological test battery is given to the same subject. Correlation between paper and pen and equivalent computerized test is calculated as a validity measure.
  • Reliability
    • Time Frame: More than 7 days, within 2 months
    • The computerized test battery is given to the same subject twice. Correlation between the two tests is calculated as a test-retest reliability measure.
  • Feasibility
    • Time Frame: Within 24 h
    • Patients under the investigation for INPH are given the computerized test battery. Number of patients who manage to complete the test is the feasibility measure.

Participating in This Clinical Trial

Inclusion Criteria

  • Probable INPH under investigation – Healthy elderly – Various diseases Exclusion Criteria:

  • (Healthy elderly) medications affecting nervous system – (Healthy elderly)heart disease – (Healthy elderly)diabetes – (Healthy elderly)disease of the nervous system – (Healthy elderly)MMSE < 28 – (Healthy elderly)vascular risk factors (Two of: 1 hypertension, 2 smoking or 3 hyperlipidemia) – (Healthy elderly)serious disease that may shorten life expectancy – (Various diseases) Affected motor functions

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Umeå University
  • Provider of Information About this Clinical Study
    • Anders Behrens M.D., Department of Clinical Neuroscience
  • Overall Official(s)
    • Anders Behrens, M.D., M.Sc., Principal Investigator, Department of Clinical Neuroscience

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