Effect of Adaptive Servoventilation on Cardiac Function in Chronic Heart Failure and Cheyne-Stokes Respiration

Overview

Sleep disordered breathing is common in patients with chronic heart failure. Adaptive servoventilation is a novel method of treatment central sleep apnoea, especially associated with Cheyne-Stokes-respiration. The aim of the study is to investigate effect of adaptive servoventilation on cardiac function, exercise tolerance and quality of life in patients with chronic heart failure.

Full Title of Study: “Effect of Adaptive Servoventilation on Cardiac Function, Exercise Tolerance and Quality of Life in Patients With Chronic Heart Failure and Cheyne-Stokes Respiration”

Study Type

  • Study Type: Interventional

Interventions

  • Device: Adaptive servoventilation
    • Background expiratory positive airway pressure with some inspiratory pressure support when needed

Arms, Groups and Cohorts

  • Experimental: ASV

Participating in This Clinical Trial

Inclusion Criteria

  • chronic heart failure with ejection fraction ≤45% – optimal medical treatment for at least 1 month – clinical diagnosis of Cheyne-Stokes respiration Exclusion Criteria:

  • unstable heart failure – stroke – transient ischemic attack in last 6 months – pacemaker, cardioverter-defibrillator or resynchronization device implanted less than 6 months before study entrance – severe chronic obstructive pulmonary disease

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Investigator Details

  • Lead Sponsor
    • Military Institute od Medicine National Research Institute
  • Overall Official(s)
    • Anna Kazimierczak, Principal Investigator, Military Institute of Medicine
  • Overall Contact(s)
    • Anna Kazimierczak, 48 22 6818017, annakazimierczak@poczta.onet.pl

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.