Study of Biomarker From Blood and Tissue of Head and Neck Carcinoma

Overview

The aim of the study is to find for one or more serum or tissue markers of molecular biology in head and neck cancer patients used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy

Full Title of Study: “Study of Previously Collected Blood and Tissue Samples From Patients With Nasopharyngeal Carcinoma,Laryngeal Carcinoma and Hypopharyngeal Carcinoma”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: December 2011

Detailed Description

Head and neck malignant tumors, especially nasopharyngeal carcinoma in southern China with the high incidence, its incidence, treatment, prognosis or tumor markers in serum has been a hot research with little progress.In our study, we collect NPC-based collection including the blood samples of laryngeal, hypopharyngeal cancer, separating serum and white blood cells stored in -80 degrees,while tissues are frozen in liquid nitrogen and embedded in paraffin。 Patient treatment and prognosis are combined in order to find for markers of molecular biology used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy.

Participating in This Clinical Trial

Inclusion Criteria

  • all of nasopharyngeal carcinoma – hypopharyngeal carcinoma or laryngeal carcinoma visited at ENT department of NanFang hospital Exclusion Criteria:

  • all of above patients whose anticipated survival duration were less than 6 months

Gender Eligibility: All

Minimum Age: 15 Years

Maximum Age: 75 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Southern Medical University, China
  • Provider of Information About this Clinical Study
    • E.N.T department of Nan Fang Hospital, Nan Fang Medical University, China: National Natural Science Foundation
  • Overall Official(s)
    • Ping Xiang Li, doctor, Study Director, E.N.T department of NanFang hospital

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