Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential
Overview
According to the National Burn Repository 2007, the most common type of burn injury is a partial thickness burns. The current standard of care for partial thickness burns is two weeks of topical therapy and wound care. Burns that do not heal within two weeks undergo surgical excision and skin grafting.
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: February 2026
Detailed Description
Researcher can use the combination of Modulated Imaging and Laser Speckle Imaging can be used as an adjuvant to standard clinical evaluation to gauge burn wound and severity of infection. Researcher can image the burn wounds of and compare with current standard of care, clinical exam, and can use the outcomes information in terms of time to healing and treatment Modulating Imaging is a noninvasive optical modality measure the metabolic functions of the burn wound. Laser Speckle Imaging is a noninvasive optical modality can measure blood flow of burn wound.
Interventions
- Device: Modulated Imaging and Laser Speckle Imaging
- wound healing
Arms, Groups and Cohorts
- Burn wound
- Modulated Imaging and Laser Speckle Imaging
Clinical Trial Outcome Measures
Primary Measures
- Noninvasive burn wound severity assessment
- Time Frame: 1 day
- Noninvasive burn wound severity assessment using noncontact optical device
Participating in This Clinical Trial
Inclusion Criteria
1. Male / female all age 2. Subjects is an inpatient or out patient with burn wound Exclusion Criteria:
1. Subjects cannot lied flat and still for the duration of the imaging 2. Subjects pregnant.
Gender Eligibility: All
Minimum Age: 1 Minute
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- University of California, Irvine
- Collaborator
- National Institute of General Medical Sciences (NIGMS)
- Provider of Information About this Clinical Study
- Principal Investigator: Anthony Joseph Durkin, Associate Professor, Director, Laboratory for Functional Imaging and Spectroscopy of Superficial Tissues – University of California, Irvine
- Overall Official(s)
- Anthony Durkin, PhD, Principal Investigator, University of California, Irvine
- Overall Contact(s)
- Gordon Kennedy, PhD, 949-824-4713, gordon.kennedy@uci.edu
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