Psychological Symptoms Among Adolescents Enrolled in a Bariatric Surgery Program

Overview

This study will examine the interaction of psychological factors and serious overweight to determine if particular patterns of psychological symptoms are helpful in predicting outcomes of weight loss surgery. Patients from the Center of Adolescent Bariatric Surgery (CABS) program at the Morgan Stanley Children's Hospital of New York Presbyterian will be asked to participate in a longitudinal prospective study of psychopathology among severely obese adolescents. Additionally, the psychological symptoms of this group will be compared to other treatment-seeking obese adolescents. The investigators hypothesize that: 1. Adolescents receiving bariatric surgery will demonstrate significant reductions in body weight, eating pathology, and other symptoms after receiving bariatric surgery. 2. Adolescents enrolled in the bariatric surgery program will report more psychological problems than other treatment-seeking obese adolescents.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: January 2017

Detailed Description

With increasing rates of overweight and obesity among children and adolescents in the United States, there is an urgent need for effective weight loss treatments for younger patients. Recently, bariatric surgery has been considered as a treatment for seriously overweight adolescents because of the potential for substantial decreases in weight and subsequent improvements in physical health. This study will examine the interaction of psychological factors and serious overweight to determine if particular patterns of psychological symptoms (psychological phenotypes) are helpful in predicting outcomes of bariatric surgery. Patients from the Center for Adolescent Bariatric Surgery (CABS) program at the Morgan Stanley Children's Hospital of New York Presbyterian will be asked to participate in a longitudinal prospective study of psychopathology among severely obese adolescents. The final aim of this project is to compare psychological symptoms between obese adolescents seeking bariatric surgery, other treatment-seeking obese adolescents, and normal-weight comparison adolescents. We will evaluate the effect of psychiatric symptoms on adherence to postsurgery follow-up appointments and weight loss. This research will be broadly applicable to the study of interactions between psychological factors and compliance with treatment for youth with chronic health conditions.

Arms, Groups and Cohorts

  • Adolescent Surgical Candidates
    • Adolescents at the Center for Adolescent Bariatric Surgery, Columbia University Medical Center
  • Obese Treatment-Seeking Adolescents
    • Obese Treatment-Seeking Adolescents, Maxcor Program for Overweight Education and Reduction (POWER) Program
  • Normal-Weight Adolescents
    • Normal-Weight Adolescents

Clinical Trial Outcome Measures

Primary Measures

  • Psychological Symptoms
    • Time Frame: 8 assessment points: (1) baseline pre-surgery, (2) 2 weeks pre-surgery, (3) 3 months post-surgery, (4) 6 months post-surgery, (5) 9 months post-surgery, (6) 12 months post-surgery, (7) 18 months post-surgery, (8) 24 months post-surgery
    • The measures of psychological symptoms at each time point will include: Eating and Activity Measures Depressive Symptom Measures Impulsivity Measures Measures of other relevant factors, including body mass index, family functioning, and quality of life.

Secondary Measures

  • Treatment Compliance
    • Time Frame: 8 assessment points: (1) Baseline pre-surgery, (2) 2 weeks pre-surgery, (3) 3 months post-surgery, (4) 6 months post-surgery, (5) 9 months post-surgery, (6) 12 months post-surgery, (7) 18 months post-surgery, (8) 12 months post-surgery
    • Clinician rated measures of compliance and adherence to treatment recommendations.

Participating in This Clinical Trial

Longitudinal assessments: Inclusion Criteria:

  • enrolled in the Center for Adolescent Bariatric Surgery (CABS) at the Morgan Stanley Children's Hospital of New York Presbyterian – entered the CABS program between the ages of 12 and 17, between the ages of 12 and 18 when entering the study – adolescents speak English – parents speak English or Spanish Exclusion Criteria:

  • DSM-IV Diagnosis of Mild, Moderate, or Severe Mental Retardation (e.g., IQ < 70) CONTROL GROUP (obese treatment-seeking adolescents) Inclusion Criteria:

  • enrolled in the Maxcor Program for Overweight Education and Reduction (POWER) Program – Between the ages of 14 and 18 – adolescents speak English – parents speak English or Spanish Exclusion Criteria:

  • DSM-IV Diagnosis of Mild, Moderate, or Severe Mental Retardation (e.g., IQ < 70) CONTROL GROUP (normal-weight adolescents) Inclusion Criteria:

  • body mass index between 25th and 85th percentile for sex – between the ages of 14 and 18 – adolescents speak English – parents speak English Exclusion Criteria:

  • DSM-IV Diagnosis of Mild, Moderate, or Severe Mental Retardation (e.g., IQ < 70)

Gender Eligibility: All

Minimum Age: 12 Years

Maximum Age: 18 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • New York State Psychiatric Institute
  • Provider of Information About this Clinical Study
    • Principal Investigator: Leora David, Research Scientist – New York State Psychiatric Institute
  • Overall Official(s)
    • Robyn Sysko, Ph.D., Principal Investigator, New York State Psychiatric Institute

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