Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function
Overview
Aim of the present study is twofold. – First we want to evaluate the effect of mobilization on acute postoperative pain – Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total knee arthroplasty
Full Title of Study: “Effect of Mobilization on Acute Postoperative Pain and Nociceptive Function After Total Knee Arthroplasty: A Prospective, Consecutive, Trial”
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: June 2010
Detailed Description
Little is known about the effect of mobilization on acute postoperative pain and mobilization induced pain, and if altered pain sensitivity occur under these circumstances. – First we want to evaluate the effect of mobilization on acute postoperative pain using the visual analog scale (VAS) – Second to test weather chances in pain sensitivity are occurring following surgery and mobilization after total knee arthroplasty, using two simple tools, the Pain Matcher and a Pressure Algometer.
Interventions
- Other: Mobilization (walking)
- 25 meters twice
Clinical Trial Outcome Measures
Primary Measures
- Pain score on the visual analog scale (difference before and after two mobilisation seances)
- Time Frame: up to 24 hours
- pain at rest (supine) 5 min after exercise(after the 2nd walk)
Secondary Measures
- Pain score on the visual analog scale (difference before and after two mobilisation seances)
- Time Frame: up to 24 hours
- pain at rest (supine) 20 min after the 2nd walk, pain during passive hip flexion and pain during passive knee flexion 5 and 20 min after the 2nd walk, as well as pain during the 2nd walk after 6 and 25 m
- Pain sensitivity measured with pressure algometry and with pain matcher (difference before and after two mobilisation seances and difference before and after surgery)
- Time Frame: up to 24 hours
- Nociceptive function before and after postoperative exercise
Participating in This Clinical Trial
Inclusion Criteria
- Patients scheduled for total unilateral knee arthroplasty Exclusion Criteria:
- Cognitive dysfunction or peripheral / central neurological dysfunction inconsistent with protocol completing – Alcohol and medical abuse (as defined by the National Health Service of Denmark – Daily use of opioids or glucocorticoids
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- Hvidovre University Hospital
- Collaborator
- Lundbeck Foundation
- Provider of Information About this Clinical Study
- Principal Investigator: Troels Haxholdt Lunn, MD – Hvidovre University Hospital
- Overall Official(s)
- Troels Haxholdt Lunn, MD, Principal Investigator, Hvidovre University Hospital
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