The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver.
Full Title of Study: “Identification of New Biomarkers of Drug Induced Liver Injury”
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: December 2013
Our hypothesis is that there are liver-specific particles, called mRNA, that are identifiable in a person's blood sample during liver injury caused by some drugs. The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver, perhaps early in the process before significant injury or illness have occurred.
Arms, Groups and Cohorts
- Acute drug-induced liver injury
Participating in This Clinical Trial
- ALT > 200 IU/L at presentation to UNC Hospitals
- Drug induced liver injury considered likely by admitting medical staff
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 80 Years
Are Healthy Volunteers Accepted: No
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Provider of Information About this Clinical Study
- Overall Official(s)
- Paul B Watkins, MD, Principal Investigator, University of North Carolina, Chapel Hill
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