Cytokine Levels in Conversion Disorder
Overview
The aim of this study is whether the proinflammatory cytokine levels in patients with conversion disorder is increased or not changed in the acute phase and subacute – chronic periode, compared with controls.
Full Title of Study: “Proinflammatory Cytokine Levels in Patients With Conversion Disorder”
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: September 2010
Interventions
- Other: conversion disorder
- Proinflammatory cytokine levels in conversion disorder
Arms, Groups and Cohorts
- Conversion disorder
- Healthy control
Participating in This Clinical Trial
Inclusion Criteria
- Clinical diagnosis of Alzheimer's Disease Exclusion Criteria:
- Autoimmune disease – Neurological disease – Any organic disorder that could possibly affect proinflammatory cytokines – Pregnancy – Any drug usage within 2 weeks – Any active or passive immunization within 6 months – Any other DSM-IV axis I psychiatric disorder – Mental retardation – Developmental disorder of childhood
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 65 Years
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- Trakya University
- Provider of Information About this Clinical Study
- Trakya University Scientific Research Unit (TUBAB), Trakya University Scientific Research Unit (TUBAB)
References
Rief W, Pilger F, Ihle D, Bosmans E, Egyed B, Maes M. Immunological differences between patients with major depression and somatization syndrome. Psychiatry Res. 2001 Dec 31;105(3):165-74. doi: 10.1016/s0165-1781(01)00338-9.
Ziemssen T, Kern S. Psychoneuroimmunology–cross-talk between the immune and nervous systems. J Neurol. 2007 May;254 Suppl 2:II8-11. doi: 10.1007/s00415-007-2003-8. Erratum In: J Neurol. 2008 Feb;255(2):309-10.
Dantzer R. Somatization: a psychoneuroimmune perspective. Psychoneuroendocrinology. 2005 Nov;30(10):947-52. doi: 10.1016/j.psyneuen.2005.03.011.
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