Cytokine Levels in Conversion Disorder

Overview

The aim of this study is whether the proinflammatory cytokine levels in patients with conversion disorder is increased or not changed in the acute phase and subacute – chronic periode, compared with controls.

Full Title of Study: “Proinflammatory Cytokine Levels in Patients With Conversion Disorder”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: September 2010

Interventions

  • Other: conversion disorder
    • Proinflammatory cytokine levels in conversion disorder

Arms, Groups and Cohorts

  • Conversion disorder
  • Healthy control

Participating in This Clinical Trial

Inclusion Criteria

  • Clinical diagnosis of Alzheimer's Disease Exclusion Criteria:

  • Autoimmune disease – Neurological disease – Any organic disorder that could possibly affect proinflammatory cytokines – Pregnancy – Any drug usage within 2 weeks – Any active or passive immunization within 6 months – Any other DSM-IV axis I psychiatric disorder – Mental retardation – Developmental disorder of childhood

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 65 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Trakya University
  • Provider of Information About this Clinical Study
    • Trakya University Scientific Research Unit (TUBAB), Trakya University Scientific Research Unit (TUBAB)

References

Rief W, Pilger F, Ihle D, Bosmans E, Egyed B, Maes M. Immunological differences between patients with major depression and somatization syndrome. Psychiatry Res. 2001 Dec 31;105(3):165-74. doi: 10.1016/s0165-1781(01)00338-9.

Ziemssen T, Kern S. Psychoneuroimmunology–cross-talk between the immune and nervous systems. J Neurol. 2007 May;254 Suppl 2:II8-11. doi: 10.1007/s00415-007-2003-8. Erratum In: J Neurol. 2008 Feb;255(2):309-10.

Dantzer R. Somatization: a psychoneuroimmune perspective. Psychoneuroendocrinology. 2005 Nov;30(10):947-52. doi: 10.1016/j.psyneuen.2005.03.011.

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