Effects of Oxybutynin Topical Gel on Gastric Emptying

Overview

This study explores the effect of oxybutynin topical gel on gastric emptying

Full Title of Study: “Effect of Oxybutynin Chloride Topical Gel on Gastric Emptying, Using the Acetaminophen Absorption Test”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Crossover Assignment
    • Primary Purpose: Basic Science
    • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Study Primary Completion Date: July 2009

Interventions

  • Drug: Oxybutynin Chloride Gel
    • Once daily for 7 days, followed by single dose of acetaminophen
  • Drug: Placebo Gel
    • Once daily for 7 days, followed by single dose of acetaminophen

Arms, Groups and Cohorts

  • Experimental: Active OTG
  • Placebo Comparator: Placebo

Clinical Trial Outcome Measures

Primary Measures

  • The effect of oxybutynin chloride topical gel administration on gastric emptying will be assessed by comparing the single dose relative bioavailability of acetaminophen
    • Time Frame: After 7 days of treatment

Participating in This Clinical Trial

Inclusion Criteria

  • Adult, healthy, post-menopausal females Exclusion Criteria:

  • Patients for whom OTG or acetaminophen is contraindicated. – Abnormality of the GI tract. – Taking drugs that affect gastric motility.

Gender Eligibility: Female

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Watson Pharmaceuticals
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Scott Olsen, MPH, Study Director, Watson Laboratories

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.