Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial
Overview
The purpose of this study is to determine whether prize-based contingency management (prizeCM) combined with cognitive behavioral therapy (CBT) is more effective in the treatment of of cocaine-dependent patients compared to CBT only. Patients were randomized to prizeCM + CBT (experimental group) or to CBT (control group) an treated over 24 weeks. It is the first trial of this type in Europe.
Study Type
- Study Type: Interventional
- Study Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Primary Purpose: Treatment
- Masking: Single (Participant)
- Study Primary Completion Date: August 2013
Interventions
- Behavioral: Cognitive behavioral therapy (CBT)
Arms, Groups and Cohorts
- Experimental: 1
- Cognitive behavioral therapy (CBT) + prize-based contingency management (prizeCM)
- Active Comparator: 2
- Cognitive behavioral therapy (CBT)
Clinical Trial Outcome Measures
Primary Measures
- retention in treatment, cocaine abstinence
- Time Frame: 24 weeks
- cocaine abstinence: at least 3 consecutive weeks of cocaine abstinence, the maximum number of weeks of continous abstinence and proportions of cocaine-free urine samples during the entire 24-week and at 6-month follow-up.
Secondary Measures
- patients’ satisfaction with the therapy, clinical measures
- Time Frame: 24 weeks
- patients’ satisfaction with prize-based contingency management and with CBT
Participating in This Clinical Trial
Inclusion Criteria
- cocaine dependence, aged 18 or older, other dependences Exclusion Criteria:
- severe somatic, brain, or psychiatric disease, attention deficit disorders with medication methylphenidate
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 60 Years
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Provider of Information About this Clinical Study
- Principal Investigator: Sylvie Petitjean, Dr. phil – University Hospital, Basel, Switzerland
- Overall Official(s)
- Sylvie A Petitjean, Dr. phil., Principal Investigator, Psychiatric Hospital of the University of Basel
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