Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG)

Overview

To investigate the effectiveness of the newer IOP-lowering therapies, as prescribed in normal clinical practice, in larger patient numbers. Patients will be assessed at baseline, at each follow-up visit (follow-up visits are variable as per physician discretion) and at final follow-up visit.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: September 2007

Interventions

  • Drug: bimatoprost 0.03%, latanoprost 0.005%, and travoprost 0.004%
    • 1 drop in eye(s) every evening

Arms, Groups and Cohorts

  • 1
    • bimatoprost 0.03% latanoprost 0.005% travoprost 0.004%

Clinical Trial Outcome Measures

Primary Measures

  • Change From Baseline in Bilateral Intraocular Pressure (IOP) at One Year
    • Time Frame: Baseline, 1 Year
    • Change from baseline in bilateral (both eyes) IOP at the 1 year follow-up visit. IOP is a measure of the fluid pressure inside the eye. The bilateral IOP was calculated as an average between both eye’s IOP. A negative number change from baseline indicates reduction in IOP (improvement).

Participating in This Clinical Trial

Inclusion Criteria

  • A diagnosis of Primary Open-Angle Glaucoma or Ocular Hypertension newly diagnosed OR presenting with insufficiently controlled IOP on current medication (in the opinion of the treating physician) – Patient is having both eyes treated Exclusion Criteria:

  • Contraindications per product labelling will apply. – Patients with any ophthalmic co-morbidity with an influence on visual field deterioration or optic nerve head damage.

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Allergan
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Medical Director, Study Director, Allergan

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