Preoperative Heart Rate Variability and Baroreflex Sensitivity in ASO Patients During Various Sleep Stages

Overview

The goal of this study is to evaluate the possible preoperative predictive value of altered heart rate variability (HRV) and baroreflex sensitivity in different sleep stages for postoperative adverse cardiac events (i.e. arrhythmia or myocardial ischemia needing hospitalization or medication, myocardial ischemia assessed by enzyme release, myocardial infarction, sudden cardiac death, stroke) in arteriosclerosis obliterans patients.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective

Arms, Groups and Cohorts

  • 1
    • Arteriosclerosis obliterans patients undergoing elective vascular surgery
  • 2
    • Healthy age-matched volunteers

Participating in This Clinical Trial

Inclusion Criteria

  • Age > 40 years – ASO – Elective vascular surgery patient (i.e. infra-inguinal bypass procedure) Exclusion Criteria:

  • Other than sinus rhythm – Lack of co-operation – Major surgery less than 3 months preoperatively – Sleep apnoea – Dialysis treatment – CABG less than 3 years earlier

Gender Eligibility: All

Minimum Age: 40 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • GE Healthcare
  • Collaborator
    • Turku University Hospital
  • Provider of Information About this Clinical Study
    • Dr. Timo Laitio (Timo.Laitio@tyks.fi), Department of Anesthesiology and Intensive Care, Turku University Hospital
  • Overall Official(s)
    • Timo Laitio, MD, PhD, Principal Investigator, Turku University Hospital
    • Pekka Meriläinen, Prof., Study Director, GE Healthcare, Finland

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