Automated Chest Compression in Cardiac Arrest

Overview

To evaluate the effect of use of automated chest compression device on blood pressure in patients presenting with cardiac arrest. Higher systolic, diastolic and mean blood pressures are expected.

Full Title of Study: “Effect on Hemodynamics of Automated Band Chest Compression Device in Cardiac Arrest Resuscitation”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: January 2009

Detailed Description

The protocol compares arterial pressures produced by an automated self-adjusting load-distributing band device (AutoPulse™ 100, Zoll®) with those of manual cardiopulmonary resuscitation in refractory out-of-hospital cardiac arrest. Each patient will receive first manual compressions and then automated resuscitation. Patients presenting with cardiac arrest are treated following standard advanced life support guidelines. They are intubated and ventilated, received epinephrine and defibrillation if appropriate. Manuel chest compressions are continued. An arterial catheter is placed to monitor hemodynamics continuously as we usually do in this case. Patients are included at this stage. Three blood pressure values (every 1 minutes) are recorded. Then, the automated band device is started up without any pause, following our procedure for refractory cardiac arrest. Three blood pressure values are recorded again, during automated cardiopulmonary resuscitation.

Interventions

  • Device: Automated load-distributing band device
    • Blood pressure recording before and after starting up the automated band device

Clinical Trial Outcome Measures

Primary Measures

  • Diastolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient
    • Time Frame: Instantaneously

Secondary Measures

  • Systolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient
    • Time Frame: Instantaneously
  • Mean blood pressures produced by manual and then by automated chest compressions will be recorded for each patient
    • Time Frame: Instantaneously

Participating in This Clinical Trial

Inclusion Criteria

  • Age ≥ 18 – Refractory cardiac arrest Exclusion Criteria:

  • Defective invasive arterial blood pressure monitoring

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Beaujon Hospital
  • Provider of Information About this Clinical Study
    • François-Xavier Duchateau, MD, Departement of Anesthesiology, Intensive Care and EMS, Beaujon Hospital
  • Overall Official(s)
    • Francois-Xavier Duchateau, MD, Principal Investigator, Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital
    • Jean Mantz, MDPhD, Study Chair, Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital

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