Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Carbon Monoxide Poisoning


That SPECT brain imaging tracks and is consistent with clinical history and physical exam as well as cognitive testing.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: December 2018

Detailed Description

The study is a retrospective review of the PI's experience using SPECT brain imaging and hyperbaric oxygen therapy in the diagnosis and treatment of non-acute phases of carbon monoxide poisoning. The purpose is to see if the SPECT brain imaging is consistent with the clinical condition and cognitive testing on the patients.


  • Drug: HBOT
    • total body exposure to greater than atmospheric pressure oxygen

Arms, Groups and Cohorts

  • 1
    • HBOT

Clinical Trial Outcome Measures

Primary Measures

  • SPECT brain imaging
    • Time Frame: after completion of HBOT

Secondary Measures

  • clinical history and physical exam
    • Time Frame: after completion of HBOT
  • Neuropsychological testing
    • Time Frame: After the final HBOT
    • Neuropsychological testing performed after the final HBOT in those who had neuropsychological testing before HBOT

Participating in This Clinical Trial

Inclusion Criteria

  • Adults and children with non-acute carbon monoxide poisoning who underwent SPECT brain imaging as part of their evaluation and treatment

Exclusion Criteria

  • None.

Gender Eligibility: All

Minimum Age: N/A

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Paul G. Harch, M.D.
  • Collaborator
    • Harch Hyperbaric Research Foundation
  • Provider of Information About this Clinical Study
    • Sponsor-Investigator: Paul G. Harch, M.D., Clinical Professor of Medicine – Louisiana State University Health Sciences Center in New Orleans
  • Overall Official(s)
    • Paul G Harch, M.D., Principal Investigator, LSU School of Medicine
  • Overall Contact(s)
    • Paul G Harch, M.D., 504-309-4948, paulharchmd@gmail.com

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