Optical Coherence Tomography of Airway and Pleural Disorders
Overview
The researcher can use Optical coherence tomography a near-infrared diode to emit light that can produce images of the specimen under investigation and provide information about tissue abnormalities without causing damage.
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: July 2018
Detailed Description
The researcher can use Optical coherence tomography endoscopic imaging to improve diagnosis and treatment of airway and pleural malignancy. In the events of burn injury and smoke inhalation injury, the Optical coherence tomography can determine the change of the airway tissues and severity of airway injury. During endoscopic procedure the lesions will be biopsied and prepared by standard histologic methods. The Optical coherence tomography endoscopic imaging can measured histologic of the tissue samples and compared to standard histologic examination. The Optical coherence tomography endoscopic imaging can measured the epithelial thickness and compared to visual inspection of the mucosa on bronchoscopy.
Interventions
- Device: Optical Coherence Tomography imaging
- Optical Coherence Tomography imaging
Arms, Groups and Cohorts
- Airway and Pleural Disorders
- Optical Coherence Tomography imaging
Clinical Trial Outcome Measures
Primary Measures
- histopathology
- Time Frame: up to 4 weeks
Participating in This Clinical Trial
Inclusion Criteria
- Adult 18 or older, male or female. – Plans for bronchoscopic with possible biopsy procedures. Exclusion Criteria:
- Age less than 18 years of age – Not plan for bronchoscopic with possible biopsy procedures. – Pregnant or breastfeeding.
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- University of California, Irvine
- Collaborator
- Beckman Laser Institute University of California Irvine
- Provider of Information About this Clinical Study
- Principal Investigator: Beckman Laser Institute and Medical Center, Matthew Brenner, M.D.,Department of Pulmonary and Critical Care Medicine – University of California, Irvine
- Overall Official(s)
- Matthew Brenner, M.D, Principal Investigator, Beckman Laser Institute
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