The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture
Overview
The objective of the present study is to determine whether or not primary human mammary epithelial cells are competent for use in molecular studies of transepithelial electrophysiology focusing on the function of the tight junction protein claudin 3. Human breast Tissue will be removed from mastectomy specimens and used as a source to generate epithelial cells for study.
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: July 2009
Clinical Trial Outcome Measures
Primary Measures
- Cell line data study
- Time Frame: one year
Participating in This Clinical Trial
Inclusion Criteria
- Subjects of this pilot study are limited to those female patients who are undergoing therapeutic or prophylactic mastectomy procedures conducted by the department of Surgery at HUMC. Exclusion Criteria:
- From within this population, no exclusion criteria shall be applied based on age, race, ethnicity, gender, HIV status, or menopause.
Gender Eligibility: Female
Minimum Age: N/A
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- Hackensack Meridian Health
- Provider of Information About this Clinical Study
- Sponsor
- Overall Official(s)
- Erik F Young, Ph.D., Principal Investigator, Hackensack Meridian Health
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