The Use of Nasal Phenylephrine in Infants With Bronchiolitis
Overview
Drops of either saline or phenylephrine are placed in the nose of infants less than 12 months of age to determine if it helps them to breathe easier.
Full Title of Study: “A Randomized, Double-Blinded Placebo Control Trial of Nasal Phenylephrine in Infants With Bronchiolitis”
Study Type
- Study Type: Interventional
- Study Design
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Primary Purpose: Treatment
- Masking: Double
- Study Primary Completion Date: June 2005
Interventions
- Drug: Phenylephrine
Clinical Trial Outcome Measures
Primary Measures
- Respiratory Distress Assessment Index at 5 minutes, 60 minutes, and 180 minutes.
Secondary Measures
- Respiratory rate, oxygen saturation and use of supplemental oxygen at 5, 60, and 180 minutes.
Participating in This Clinical Trial
Inclusion Criteria
- Age 4 weeks to 12 months; admitting diagnosis of bronchiolitis; admitted to hospital's bronchiolitis pathway, admitted during weekdays, need for nasal suctioning. Exclusion Criteria:
- Congenital heart disease, history of hypertension, previous wheezing, prior use of inhaled corticosteroids, gestational age at birth of <34 weeks.
Gender Eligibility: All
Minimum Age: 4 Weeks
Maximum Age: 12 Months
Investigator Details
- Lead Sponsor
- Akron Children’s Hospital
- Provider of Information About this Clinical Study
- Nathan Kraynack, M.D., Akron Children’s Hospital
- Overall Official(s)
- Rachel Konda-Sundheim, MD, MD, Principal Investigator, Children’s Hospital Medical Center of Akron
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