Molecular Epidemiology of Benzene-exposed Workers.
Overview
The purpose of this study is to investigate the health effects of benzene exposure in workers in Shanghai, China.
Full Title of Study: “Molecular Epidemiology of Benzene-exposed Workers in Shanghai,China”
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Cross-Sectional
- Study Primary Completion Date: December 2009
Detailed Description
The purpose of this study is to investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers and to characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
Interventions
- Other: Shanghai workers
Arms, Groups and Cohorts
- Shanghai Workers
- Shanghai Workers
Clinical Trial Outcome Measures
Primary Measures
- Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers.
- Time Frame: August 2003 – December 2009
- Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers
Secondary Measures
- Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
- Time Frame: August 2003 – December 2009
- Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
Participating in This Clinical Trial
Inclusion Criteria
Worked for at least one year in a monitored environment Have at least one physical examination recorded - Exclusion Criteria:
History of cancer, radiation exposure, chemotherapy -
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 67 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- University of Colorado, Denver
- Collaborator
- Fudan University
- Provider of Information About this Clinical Study
- Sponsor
- Overall Official(s)
- Richard D Irons, PhD, Principal Investigator, University of Colorado at Denver and Health Sciences Ctr
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