Molecular Epidemiology of Benzene-exposed Workers.

Overview

The purpose of this study is to investigate the health effects of benzene exposure in workers in Shanghai, China.

Full Title of Study: “Molecular Epidemiology of Benzene-exposed Workers in Shanghai,China”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: December 2009

Detailed Description

The purpose of this study is to investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers and to characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.

Interventions

  • Other: Shanghai workers

Arms, Groups and Cohorts

  • Shanghai Workers
    • Shanghai Workers

Clinical Trial Outcome Measures

Primary Measures

  • Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers.
    • Time Frame: August 2003 – December 2009
    • Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers

Secondary Measures

  • Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
    • Time Frame: August 2003 – December 2009
    • Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.

Participating in This Clinical Trial

Inclusion Criteria

Worked for at least one year in a monitored environment Have at least one physical examination recorded - Exclusion Criteria:

History of cancer, radiation exposure, chemotherapy -

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 67 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • University of Colorado, Denver
  • Collaborator
    • Fudan University
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Richard D Irons, PhD, Principal Investigator, University of Colorado at Denver and Health Sciences Ctr

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