Analgesia of Fibula Free Flap Donor Site by Peri-Neuronal Catheter in Oro-Pharyngeal Carcinoma Surgery

Overview

This trial examines the analgesia of the fibula free flap donor site by peri-neuronal catheter in oro-pharyngeal carcinoma surgery by comparing continuous infusion of a local anesthetic with systemic multimodal analgesia.

Full Title of Study: “Analgesia of Fibula Free Flap Donor Site by Peri-Neuronal Catheter in Oro-Pharyngeal Carcinoma Surgery: Comparing Continuous Infusion of Local Anesthetic With Systemic Multimodal Analgesia”

Study Type

• Study Type: Interventional
• Study Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Primary Purpose: Treatment
  • Masking: Double

Interventions

• Device: Peri-Neuronal Catheter

Clinical Trial Outcome Measures

Primary Measures

• Assess the influence of locoregional anesthesia on postoperative morphine consumption

Secondary Measures

• Visual analog pain scale on the free flap donor site

Participating in This Clinical Trial

Inclusion Criteria

• Adult patients scheduled for oro-pharyngeal carcinoma surgery with reconstruction by fibula free flap Exclusion Criteria:

• Allergy to propofol or local anesthetic (ropivacaine) – Severe renal or cardiac failure

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

• Lead Sponsor
  • Gustave Roussy, Cancer Campus, Grand Paris
• Overall Official(s)
  • Frédéric Plantevin, MD, Principal Investigator, Gustave Roussy, Cancer Campus, Grand Paris
• Overall Contact(s)
  • Frédéric Plantevin, MD, 33 1 42 11 44 37, plantevin@igr.fr